Yakata H, Yokobayashi T, Nakajima T
J Oral Surg. 1979 May;37(5):314-8.
The effects on heart rate of injections of local anesthetics into the oral mucosa were studied in neuropsychiatric patients; these patients, in whom syncope had not occurred, had been hospitalized for a prolonged period. The heart rate in the neuropsychiatric patients decreased by only 3.9% in contrast to an average decrease of 12.6% in healthy adults. Diazepam was also effective in reducing the cardiac response. The lack of responsiveness in the trigeminal-vagal reflex may be a factor in protecting patients from syncope.
研究了在神经精神疾病患者口腔黏膜注射局部麻醉剂对心率的影响；这些未曾发生过晕厥且已长期住院的患者参与了研究。与健康成年人平均下降12.6%相比，神经精神疾病患者的心率仅下降了3.9%。地西泮在减轻心脏反应方面也有效。三叉神经 - 迷走神经反射缺乏反应性可能是保护患者不发生晕厥的一个因素。
