Nussinovitch Hanan, Tsumi Erez, Tuuminen Raimo, Malyugin Boris, Lior Yotam, Naidorf Rosenblatt Hadar, Boyko Matthew, Achiron Asaf, Knyazer Boris
Department of Ophthalmology, Shaarei Zedek Medical Center, Jerusalem 9103102, Israel.
Department of Ophthalmology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beersheba 8410501, Israel.
J Clin Med. 2021 Oct 11;10(20):4658. doi: 10.3390/jcm10204658.
Advancements in surgical techniques and increased life expectancy have made cataract surgery more common among very old patients. However, surgical outcomes seem impaired in patients older than 90 years, especially with ocular comorbidities. A retrospective case-control study of 53 eyes of 53 very old patients (mean 92.6 ± 3.0) and 140 eyes of 140 matched patients (mean 75.2 ± 7.6) was undertaken. Groups were matched in terms of gender and systemic and ocular comorbidities. In very old patients, higher phacoemulsification energy (cumulative dissipated energy [CDE], 25.0 ± 22.4 vs. 16.1 ± 10.7, = 0.01) and rate of intraoperative floppy iris syndrome (IFIS, 9.4% vs. 1.4%, = 0.02) were observed compared to controls. Uncorrected (UCVA) and best-corrected distance visual acuity (BCVA) gains were significantly poorer among the very old patients than among the control at postoperative day 30 (0.20 ± 0.70 vs. 0.56 ± 0.61 logMAR, < 0.001 and 0.27 ± 0.64 vs. 0.55 ± 0.62 logMAR, = 0.006, respectively). Even after including CDE and IFIS as covariates, age remained an independent factor for poor visual gain at 30 days ( < 0.001). Cataract surgery in very old patients may demand more experienced surgeons due to higher nuclear density and the rates of IFIS. Expectations in visual acuity gains should be aligned with the patient's age.
手术技术的进步和预期寿命的延长使得白内障手术在高龄患者中更为常见。然而,90岁以上患者的手术效果似乎较差,尤其是伴有眼部合并症的患者。对53例高龄患者(平均92.6±3.0岁)的53只眼和140例匹配患者(平均75.2±7.6岁)的140只眼进行了一项回顾性病例对照研究。两组在性别、全身和眼部合并症方面进行了匹配。与对照组相比,高龄患者的超声乳化能量更高(累积消散能量[CDE],25.0±22.4 vs. 16.1±10.7,P = 0.01),术中虹膜松弛综合征(IFIS)的发生率更高(9.4% vs. 1.4%,P = 0.02)。术后30天,高龄患者的未矫正(UCVA)和最佳矫正远视力(BCVA)提高明显低于对照组(分别为0.20±0.70 vs. 0.56±0.61 logMAR,P<0.001和0.27±0.64 vs. 0.55±0.62 logMAR,P = 0.006)。即使将CDE和IFIS作为协变量纳入,年龄仍然是30天时视力提高不佳的独立因素(P<0.001)。由于更高的核密度和IFIS发生率,高龄患者的白内障手术可能需要更有经验的外科医生。视力提高的预期应与患者年龄相匹配。