Wu Bin, Yuan Xiaoyong, Chen Song
Clinical College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin, China.
BMC Ophthalmol. 2021 Oct 22;21(1):375. doi: 10.1186/s12886-021-02094-z.
To compare the accuracy of low-frequency ultrasound biomicroscopy (LFUBM) and 14-MHz ultrasonography with tissue harmonic imaging (14-MHz + THI) in the assessment of posterior capsule (PC) integrity in patients with traumatic cataracts (TCs).
From January 2019 to October 2020, 51 patients (51 eyes) with TCs who were scheduled for cataract extraction and for whom the PC of the lens could not be observed by the slit lamp visited Tianjin Eye Hospital, including 47 patients (47 eyes) with a penetrating injury of the eyeball and 4 patients (4 eyes) with a blunt injury of the eyeball. All eyes underwent LFUBM and 14-MHz + THI examinations before cataract extraction to determine the integrity of the PC. The integrity of the PC observed in surgery was the actual findings, and the consistency between the 2 methods was assessed in terms of the preoperative examination and intraoperative findings. Fisher's exact test was used for consistency analysis, and P < 0.05 was considered statistically significant.
Thirty-two eyes with ruptured PCs and 19 eyes with intact PCs were actual findings in surgery. Thirty eyes with ruptured PCs and 21 eyes with intact PCs were examined by LFUBM. Thirty-two eyes with ruptured PCs and 19 eyes with intact PCs were examined by 14-MHz + THI. There were no significant differences between the 2 methods and the intraoperative findings (P = 0.293 LFUBM, P = 0.623 14-MHz + THI). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of LFUBM and 14-MHz + THI were 91 and 94%, 95 and 89%, 97 and 94%, 86 and 89% and 92 and 92%, respectively.
Both LFUBM and 14-MHz + THI were proved to have high levels sensitivity and specificity in diagnosing the status of the PC in TC and they can be used as accurate diagnostic tool in these cases.
比较低频超声生物显微镜检查（LFUBM）和14兆赫超声联合组织谐波成像（14-MHz + THI）评估外伤性白内障（TC）患者后囊膜（PC）完整性的准确性。
2019年1月至2020年10月，51例计划行白内障摘除术且裂隙灯无法观察到晶状体PC的TC患者（51只眼）就诊于天津眼科医院，其中眼球穿透伤47例（47只眼），眼球钝挫伤4例（4只眼）。所有患眼在白内障摘除术前均接受LFUBM和14-MHz + THI检查以确定PC的完整性。手术中观察到的PC完整性为实际结果，根据术前检查和术中发现评估两种方法之间的一致性。采用Fisher精确检验进行一致性分析，P < 0.05为差异有统计学意义。
手术实际发现32只眼PC破裂，19只眼PC完整。LFUBM检查出30只眼PC破裂，21只眼PC完整。14-MHz + THI检查出32只眼PC破裂，19只眼PC完整。两种方法与术中发现之间无显著差异（LFUBM的P = 0.293，14-MHz + THI的P = 0.623）。LFUBM和14-MHz + THI的灵敏度、特异度、阳性预测值、阴性预测值和准确度分别为91%和94%、95%和89%、97%和94%、86%和89%、92%和92%。
LFUBM和14-MHz + THI在诊断TC患者PC状态方面均具有较高的灵敏度和特异度，可作为这些病例的准确诊断工具。
