Selcuk University, Vocational School of Health Services, Konya, Turkey.
Istanbul University-Cerrahpasa, Florence Nightingale Nursing Faculty, Istanbul, Turkey,.
Transpl Immunol. 2021 Dec;69:101488. doi: 10.1016/j.trim.2021.101488. Epub 2021 Oct 20.
This study aims to determine the effect of navigation programme in the management of symptoms related to head and neck cancer (HNC) radiotherapy.
This randomized, controlled and experimental study was conducted between November 2018 and March 2020 with the participation of 88 patients with HNC receiving radiotherapy. Referring to the pre-prepared randomization checklist, 41 people were randomized to the experimental group and 47 to the control group. While the standard treatment approaches of the hospital were applied to all patients, the patients in the experimental group were applied an additional nursing navigation program. At the beginning of the navigation program, the patients were given a 30-minute visual training on the first day of radiotherapy and a handbook related to the expected adverse effects. Throughout subsequent seven weeks, the patient continued to be followed up via phone reminders, providing daily counseling and a weekly follow-up. Patient identification form, CTCAE v5.0 toxicity criteria and EORTC QLQ-30, H&N35 assessment questionnaires were used in the study. The first result was the difference observed in quality of life scores at the beginning, middle and end of radiotherapy.
Data obtained from the study revealed that the quality of life scores (p < 0.05) improved while the navigation program reduced the severity of symptoms such as mucositis, dysphagia, oral pain and weight loss (p < 0.05).
It was concluded that navigation programme is an effective approach for patients receiving head and neck radiotherapy.
NCT04857749.
本研究旨在确定导航方案在管理头颈部癌症(HNC)放疗相关症状中的作用。
这是一项于 2018 年 11 月至 2020 年 3 月期间进行的随机、对照和实验性研究,共有 88 名接受放疗的 HNC 患者参与。参考预先准备的随机检查表,41 人被随机分配到实验组,47 人被分配到对照组。虽然所有患者均采用医院的标准治疗方法,但实验组患者还采用了额外的护理导航方案。在导航方案开始时,患者在放疗第一天接受 30 分钟的视觉训练,并获得与预期不良反应相关的手册。在随后的七周内,通过电话提醒继续对患者进行随访,提供日常咨询和每周随访。患者识别表、CTCAE v5.0 毒性标准和 EORTC QLQ-30、H&N35 评估问卷用于本研究。第一个结果是放疗开始、中期和结束时观察到的生活质量评分差异。
研究获得的数据表明,生活质量评分(p<0.05)有所提高,而导航方案减轻了黏膜炎、吞咽困难、口腔疼痛和体重减轻等症状的严重程度(p<0.05)。
导航方案对头颈部放疗患者有效。
NCT04857749。