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吸烟、血脂与血管造影评估的冠状动脉疾病

Cigarette smoking, serum lipids and angiographically-assessed coronary artery disease.

作者信息

Thevenin M, Barcellos G A, Dumont G

出版信息

Arch Toxicol Suppl. 1986;9:120-3. doi: 10.1007/978-3-642-71248-7_14.

Abstract

Seventy-six patients underwent cardiac catheterization for evaluation of suspected coronary artery disease and their serum lipid fractions and cigarette smoking habits were evaluated in order to determine the incidence of these risk factors on coronary artery disease. Results showed that patients with angiography defined coronary artery disease (CAD) presented disturbances in their serum lipid fractions, especially LDL-cholesterol, apoprotein B and the ratio HDL-C/(TC-HDL-C). Coronary lesions from smokers were higher when compared with matched non smokers with CAD. Cessation of smoking for two years did not induce regression of CAD among past smokers.

摘要

76例患者因疑似冠状动脉疾病接受了心导管检查,并对其血脂成分和吸烟习惯进行了评估,以确定这些危险因素在冠状动脉疾病中的发生率。结果显示,血管造影确诊为冠状动脉疾病(CAD)的患者血脂成分出现异常,尤其是低密度脂蛋白胆固醇、载脂蛋白B和高密度脂蛋白胆固醇/(总胆固醇-高密度脂蛋白胆固醇)比值。与匹配的非吸烟CAD患者相比,吸烟患者的冠状动脉病变更严重。既往吸烟者戒烟两年并未使CAD病情逆转。

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