Rozman K, Strassle B, Iatropoulos M J
Arch Toxicol Suppl. 1986;9:356-60. doi: 10.1007/978-3-642-71248-7_68.
This paper demonstrates by electron microscopy that interscapular brown adipose tissue (IBAT) is a target tissue of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats. Because of the known importance of IBAT in energy metabolism, it is suggested that brown adipose tissue may be a major target tissue in the toxicity of TCDD.
本文通过电子显微镜证明,肩胛间棕色脂肪组织(IBAT)是大鼠体内2,3,7,8-四氯二苯并对二恶英(TCDD)的靶组织。鉴于IBAT在能量代谢中的已知重要性,有人提出棕色脂肪组织可能是TCDD毒性作用的主要靶组织。