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神经调节作为脊髓损伤后神经保护和修复的基本平台。

Neuromodulation as a basic platform for neuroprotection and repair after spinal cord injury.

机构信息

Department of Fundamental Medicine, School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia.

Department of Neurosurgery, Medical Center, Far Eastern Federal University, Vladivostok, Russia.

出版信息

Prog Brain Res. 2021;266:269-300. doi: 10.1016/bs.pbr.2021.06.012. Epub 2021 Oct 6.

Abstract

Spinal cord injury (SCI) is one of the most challenging medical issues. Spasticity is a major complication of SCI. A combination of spinal cord stimulation, new methods of neuroprotection and biomedical cellular products provides fundamentally new options for SCI treatment and rehabilitation. The paper attempts to critically analyze the effectiveness of using these procedures for patients with SCI, suggesting a protocol for a step-by-step personalized treatment of SCI, based on continuity of modern conservative and surgical methods. The study argues the possibility of using neuromodulation as a basis for rehabilitating patients with SCI.

摘要

脊髓损伤(SCI)是最具挑战性的医学问题之一。痉挛是 SCI 的主要并发症。脊髓刺激、神经保护的新方法和生物医学细胞产品的结合为 SCI 的治疗和康复提供了全新的选择。本文试图批判性地分析这些方法对 SCI 患者的有效性,提出了一种基于现代保守和手术方法连续性的 SCI 分步个体化治疗方案。该研究提出了将神经调节作为 SCI 患者康复基础的可能性。

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