To Stop the Seizure, You Must Become the Seizure: Closed-Loop Stimulation Phase Locked to Seizure Waves Disrupts Kindled Seizures While Open-Loop Stimulation Fails.
作者信息
Christenson Wick Zoé, Shuman Tristan
出版信息
Epilepsy Curr. 2021 May 10;21(4):293-294. doi: 10.1177/15357597211014187. eCollection 2021 Jul-Aug.
Abstract
摘要
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To Stop the Seizure, You Must Become the Seizure: Closed-Loop Stimulation Phase Locked to Seizure Waves Disrupts Kindled Seizures While Open-Loop Stimulation Fails.要阻止癫痫发作，你必须成为癫痫发作：与癫痫波锁相的闭环刺激可扰乱点燃式癫痫发作，而开环刺激则无效。
Epilepsy Curr. 2021 May 10;21(4):293-294. doi: 10.1177/15357597211014187. eCollection 2021 Jul-Aug.
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本文引用的文献
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Medial septal GABAergic neurons reduce seizure duration upon optogenetic closed-loop stimulation.光遗传闭环刺激减少内侧隔 GABA 能神经元癫痫持续时间。
Brain. 2021 Jun 22;144(5):1576-1589. doi: 10.1093/brain/awab042.
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Closed-loop stimulation of the medial septum terminates epileptic seizures.电刺激中脑导水管周围灰质终止癫痫发作
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Desynchronization of temporal lobe theta-band activity during effective anterior thalamus deep brain stimulation in epilepsy.癫痫患者进行有效的丘脑前深部脑刺激时颞叶θ波段活动的去同步化。
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Virtual Cortical Resection Reveals Push-Pull Network Control Preceding Seizure Evolution.虚拟皮质切除术揭示癫痫发作演变前的推挽式网络控制。
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Specific impairment of "what-where-when" episodic-like memory in experimental models of temporal lobe epilepsy.实验性颞叶癫痫模型中“什么-哪里-何时”情节记忆的特定损伤。
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Synchronization and desynchronization in epilepsy: controversies and hypotheses.癫痫的同步和去同步：争议和假说。
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Responsive cortical stimulation for the treatment of medically intractable partial epilepsy.反应性皮质刺激治疗药物难治性部分性癫痫。
Neurology. 2011 Sep 27;77(13):1295-304. doi: 10.1212/WNL.0b013e3182302056. Epub 2011 Sep 14.
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Cortical projection patterns of the medial septum-diagonal band complex.内侧隔核 - 斜角带复合体的皮质投射模式。
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