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闭合楔形高位胫骨截骨术后深静脉血栓形成的模式、分布及其对临床结局的影响

Patterns and Distribution of Deep Vein Thrombosis and Its Effects on Clinical Outcomes After Opening-Wedge High Tibial Osteotomy.

作者信息

Park Hyung Jun, Kang Seung-Baik, Park Jisu, Chang Moon Jong, Kim Tae Woo, Chang Chong Bum, Choi Byung Sun

机构信息

Department of Orthopedic Surgery, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.

Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

出版信息

Orthop J Sports Med. 2021 Oct 20;9(10):23259671211030883. doi: 10.1177/23259671211030883. eCollection 2021 Oct.

Abstract

BACKGROUND

Although a few studies have reported the incidence of deep vein thrombosis (DVT) after opening-wedge high tibial osteotomy (OWHTO), previous studies focused only on symptomatic DVT. Information is lacking regarding the overall incidence of DVT after OWHTO, thrombus location, and the relationship between DVT and clinical outcome.

PURPOSE

To determine the overall incidence of DVT and classify the location of DVT after OWHTO. We also determined whether significant differences in clinical improvement exist in patients with and without DVT at 6 months and at 2 years after OWHTO.

STUDY DESIGN

Case-control study; Level of evidence, 3.

METHODS

This study included 46 patients (47 knees) who underwent OWHTO. All patients were instructed to perform knee range of motion exercises and partial weightbearing after drain removal. None of the patients received a chemoprophylaxis for DVT except intermittent pneumatic compression. DVT was diagnosed using 128-row multidetector computed tomography performed before discharge on the fourth postoperative day. The location was classified into 6 segments in the distal portion (muscular and axial veins) and proximal portion (popliteal, femoral, and common femoral veins and veins located above the iliac vein). International Knee Documentation Committee (IKDC) score was assessed preoperatively and postoperatively at 6 months, 1 year, and 2 years using a linear mixed model.

RESULTS

Although the incidence of symptomatic DVT was 8.5% (n = 4), the overall incidence of early DVT was 44.7% (n = 21). All DVTs were located in the distal portion of the lower extremity vein, and 76.2% of the DVTs were located in an axial vein. The IKDC scores were 33.6 ± 7.2 and 35.3 ± 9.1 ( = .910) preoperatively, 38.1 ± 5.6 and 40.6 ± 8.4 ( = .531) at 6 months after surgery, and 44.8 ± 6.9 and 45.9 ± 11.4 ( = .786) at 2 years after surgery in patients without and those with DVT, respectively.

CONCLUSION

The overall incidence of early DVT after OWHTO was 44.7%. DVT after OWHTO was found particularly around the osteotomy site (76.2%). Patients with DVT did not have inferior short-term clinical outcomes after surgery.

摘要

背景

尽管有几项研究报告了开放性楔形高位胫骨截骨术(OWHTO)后深静脉血栓形成(DVT)的发生率,但先前的研究仅关注有症状的DVT。关于OWHTO后DVT的总体发生率、血栓位置以及DVT与临床结局之间的关系,目前尚缺乏相关信息。

目的

确定OWHTO后DVT的总体发生率并对DVT的位置进行分类。我们还确定了OWHTO后6个月和2年时,有DVT和无DVT的患者在临床改善方面是否存在显著差异。

研究设计

病例对照研究;证据等级,3级。

方法

本研究纳入了46例(47膝)接受OWHTO的患者。所有患者在拔除引流管后均被指导进行膝关节活动度锻炼和部分负重。除间歇性气动压迫外,所有患者均未接受DVT化学预防。在术后第4天出院前,使用128排多层螺旋计算机断层扫描诊断DVT。血栓位置分为远端部分(肌肉和轴静脉)和近端部分(腘静脉、股静脉、股总静脉以及髂静脉以上的静脉)的6个节段。术前以及术后6个月、1年和2年,使用线性混合模型评估国际膝关节文献委员会(IKDC)评分。

结果

尽管有症状DVT的发生率为8.5%(n = 4),但早期DVT的总体发生率为44.7%(n = 21)。所有DVT均位于下肢静脉的远端部分,76.2%的DVT位于轴静脉。术前,无DVT患者和有DVT患者的IKDC评分分别为33.6±7.2和35.3±9.1(P = 0.910);术后6个月分别为38.1±5.6和40.6±8.4(P = 0.531);术后2年分别为44.8±6.9和45.9±11.4(P = 0.786)。

结论

OWHTO后早期DVT的总体发生率为44.7%。OWHTO后的DVT尤其多见于截骨部位周围(76.2%)。有DVT的患者术后短期临床结局并不差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b87/8532235/ba3ae60656bf/10.1177_23259671211030883-fig1.jpg

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