Yamada Gohei, Toyoda Takanari, Katada Eiichi, Matsukawa Noriyuki
Department of Neurology, Nagoya City University West Medical Center, Aichi, Japan.
Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
Clin Park Relat Disord. 2021 Oct 7;5:100111. doi: 10.1016/j.prdoa.2021.100111. eCollection 2021.
A 41-year-old woman who had been taking paroxetine began taking tramadol for bilateral ankle pain. A few days later, the patient presented acutely with both feet tremors. During a mental arithmetic task, index-finger pointing posture briefly appeared on the left side. Co-administration of paroxetine and tramadol increases the risk of serotonin toxicity. This is the first reported case of index-finger pointing posture which was associated with serotonin toxicity.
一名41岁一直在服用帕罗西汀的女性开始服用曲马多来治疗双侧踝关节疼痛。几天后,患者急性出现双脚震颤。在一项心算任务中,左侧短暂出现食指指向姿势。帕罗西汀和曲马多联合使用会增加5-羟色胺中毒的风险。这是首例报告的与5-羟色胺中毒相关的食指指向姿势病例。