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反复免疫介导的非感染性心内膜炎，需进行5次二尖瓣置换术。

Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements.

作者信息

Muller Steven A, Leavis Helen L, Taha Karim, Koenderman Leo, Chamuleau Steven A J, Suyker Willem J L, Cramer Maarten J

机构信息

Department of Cardiology, Division Heart and Lung, University Medical Center Utrecht, Utrecht, the Netherlands.

Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.

出版信息

JACC Case Rep. 2021 Oct 6;3(13):1483-1488. doi: 10.1016/j.jaccas.2021.07.034.

DOI:10.1016/j.jaccas.2021.07.034
PMID:34693347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8511474/
Abstract

We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. ().

摘要

我们报告了一名年轻患者，由于反复发生免疫介导的非感染性心内膜炎，不得不接受5次二尖瓣置换术（MVR）。该患者接受了多种抗炎药物和高剂量泼尼松治疗。在第五次二尖瓣置换术后，经过22个月的随访，患者使用阿那白滞素后病情保持稳定。（）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/1c59d39e1467/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/112aec9fc47d/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/f6e646eedc15/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/225e83103d02/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/1c59d39e1467/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/112aec9fc47d/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/f6e646eedc15/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/225e83103d02/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b6/8511474/1c59d39e1467/gr3.jpg

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