Froines Colin P, Connor Nathe, Li Emily, Yoda Rebecca A, Gonzalez-Cuyar Luis F, Lu G Nina, Fu Roxana, Zhang Matthew
Department of Ophthalmology, University of Washington School of Medicine, Seattle, Washington, USA.
Department of Ophthalmology, University of Washington, Seattle, Washington, USA.
Orbit. 2023 Jun;42(3):295-298. doi: 10.1080/01676830.2021.1990968. Epub 2021 Oct 25.
While a rare ophthalmic pathogen, infections from spp. are increasingly identified and have been associated with catastrophic vision loss. In this case report we present a previously undescribed manifestation of the melanin-producing fungus to the lower eyelid, establish an effective treatment, and review related cases. Previous cases of ophthalmic were confined to the cornea and included iatrogenic tissue trauma. This case shares neither associations however includes a remote SJS history that likely led to changes in conjunctival tissue integrity. Previous cases of spp. infecting the eyelid both included surgical source control and adjuvant antibiotic. In this case, topical therapy was deferred due to SJS-related ocular cicatricial disease. Fortunately, a full resolution was achieved with surgical resection and oral antifungal treatment.
虽然 属是一种罕见的眼科病原体,但由该属引起的感染越来越多地被发现,并且与灾难性视力丧失有关。在本病例报告中,我们介绍了一种此前未描述过的产黑色素真菌在下眼睑的表现,确立了有效的治疗方法,并回顾了相关病例。先前的眼科 病例局限于角膜,包括医源性组织创伤。然而,本病例既无上述关联因素,却有既往史史蒂文斯-约翰逊综合征(SJS),这可能导致结膜组织完整性发生改变。先前 属感染眼睑的病例均采用了手术源控制和辅助抗生素治疗。在本病例中,由于与SJS相关的眼部瘢痕性疾病,推迟了局部治疗。幸运的是,通过手术切除和口服抗真菌治疗实现了完全康复。