Ficarra G, Hansen L S, Engebretsen S, Levin L S
Oral Surg Oral Med Oral Pathol. 1987 Feb;63(2):196-201. doi: 10.1016/0030-4220(87)90312-4.
Pigmented nevi are uncommon oral lesions. We report the clinical and microscopic features of three cases of combined nevus, characterized by the association of an intramucosal nevus and a common blue nevus. Two cases were clinically suspected to be melanoma. The lesions were located on the maxillary gingiva, the mandibular gingiva, and the mucosa of the left posterior portion of the hard palate. Combined nevi of the skin vary considerably in histologic appearance. The microscopic findings demonstrated by oral combined nevi also appear to exhibit substantial histologic variation. The oral combined nevus should be differentiated from malignant melanoma by histopathologic means for, as in the skin, it appears to be clinically benign.
色素痣是罕见的口腔病变。我们报告了3例复合痣的临床和显微镜特征，其特点是黏膜内痣与普通蓝痣并存。2例临床上怀疑为黑色素瘤。病变位于上颌牙龈、下颌牙龈和硬腭左后部黏膜。皮肤复合痣的组织学表现差异很大。口腔复合痣的显微镜检查结果似乎也显示出明显的组织学差异。口腔复合痣应通过组织病理学方法与恶性黑色素瘤相鉴别，因为在临床上它似乎是良性的，就像皮肤复合痣一样。
