Department of General and Visceral Surgery, Krankenhaus Barmherzige Brüder, Regensburg, Germany;
Department of Obstetrics and Gynecology, Krankenhaus Barmherzige Brüder, Klinik St. Hedwig, Regensburg, Germany.
In Vivo. 2021 Nov-Dec;35(6):3591-3596. doi: 10.21873/invivo.12664.
BACKGROUND/AIM: Malignant struma ovarii is an extremely rare tumor entity among ovarian tumors. In the presence of ascites and peritoneal metastases, the preoperative appearance may resemble the most common epithelial ovarian carcinoma (EOC) and accordingly, the surgical therapy may be identical if a preoperative histology diagnosis is not possible. The objective of this case report is to present a patient with histopathologically confirmed malignant struma ovarii who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS and HIPEC) with the aim of complete tumor resection.
This study reports on a patient with preoperatively proven peritoneal metastasis of an 18 cm ovarian tumor with large struma ovarii and papillary thyroid carcinoma within the struma, who was treated with CRS and HIPEC after neoadjuvant chemotherapy.
This disease has a significantly better prognosis than EOC, however, HIPEC could provide an additional effect in examining the presence of peritoneal metastasis.
背景/目的:卵巢恶性甲状腺肿是卵巢肿瘤中一种极其罕见的肿瘤实体。在存在腹水和腹膜转移的情况下,术前表现可能类似于最常见的上皮性卵巢癌(EOC),因此,如果无法进行术前组织学诊断,则手术治疗可能相同。本病例报告的目的是介绍一例经组织病理学证实的恶性甲状腺肿卵巢患者,该患者接受了细胞减灭术和腹腔热灌注化疗(CRS 和 HIPEC),以期完全切除肿瘤。
本研究报告了一例术前证实存在腹膜转移的患者,该患者的卵巢肿瘤为 18 厘米,伴有大的甲状腺肿和甲状腺内的乳头状甲状腺癌,在新辅助化疗后接受了 CRS 和 HIPEC 治疗。
与 EOC 相比,这种疾病的预后明显更好,然而,HIPEC 可以在检查腹膜转移的存在方面提供额外的效果。