Alsyouf Muhannad, Daneshmand Siamak
USC Department of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Curr Opin Urol. 2022 Jan 1;32(1):24-30. doi: 10.1097/MOU.0000000000000938.
Retroperitoneal lymph node dissection (RPLND) and retroperitoneal tumor resection for germ cell cancer are complex operations requiring experience and expertise in surgical techniques necessary to achieve complete resection while minimizing morbidity. This article reviews the intricacies of RPLND for testis cancer.
Surgical management of advanced testis cancer begins with an intimate understanding of retroperitoneal anatomy and the various techniques necessary to safely extirpate tumors. Preoperatively patients should undergo comprehensive counseling and obtain up-to-date imaging along with tumor markers to assist in surgical planning and evaluation of extraretroperitoneal (ERP) disease. Surgeons must be well versed in nerve-sparing techniques to maintain ejaculatory function. Newer techniques using a midline extraperitoneal technique minimizes morbidity and length of hospital stay. Special consideration should be given to the possibility of encountering ERP disease in advanced germ cell tumors, with management of these cases in tertiary care centers with multidisciplinary teams.
The perioperative care of the testis cancer patient undergoing RPLND is complex. The goal is to achieve complete resection to render patients disease free while minimizing surgical and long-term morbidity. Advanced testis cancer patients should be managed at tertiary care facilities with surgical expertise and access to multidisciplinary care.
对于生殖细胞癌,腹膜后淋巴结清扫术(RPLND)和腹膜后肿瘤切除术是复杂的手术,需要在手术技术方面具备经验和专业知识,以实现完整切除并将发病率降至最低。本文综述了睾丸癌RPLND的复杂性。
晚期睾丸癌的手术治疗始于对腹膜后解剖结构以及安全切除肿瘤所需的各种技术的深入了解。术前,患者应接受全面的咨询,并获取最新的影像学检查结果以及肿瘤标志物,以协助手术规划和评估腹膜外(ERP)疾病。外科医生必须精通保留神经的技术以维持射精功能。采用中线腹膜外技术的新技术可将发病率和住院时间降至最低。对于晚期生殖细胞肿瘤中遇到ERP疾病的可能性应给予特别考虑,这些病例应由多学科团队在三级护理中心进行管理。
接受RPLND的睾丸癌患者的围手术期护理很复杂。目标是实现完整切除,使患者无疾病,同时将手术和长期发病率降至最低。晚期睾丸癌患者应在具备手术专业知识且能提供多学科护理的三级护理机构接受治疗。