Department of Plastic and Reconstructive Surgery, Queensland Children's Hospital, Raymond Terrace, South Brisbane, Australia.
J Craniofac Surg. 2021 Oct 1;32(7):e680-e682. doi: 10.1097/SCS.0000000000007939.
Focal thinning of the calvarial bones unrelated to an underlying systemic disease is uncommon. Of such cases documented in the medical literature, most are bilateral parietal bone thinning, which tends to affect elderly females and results in bilateral symmetric, regularly shaped depressions of the skull. The authors describe 2 cases of unilateral, focal, irregularly shaped calvarial thinning in adolescent males that occurred without an obvious precipitating incident and were unrelated to systemic disease, a known syndrome or previous trauma. The nature and physical parameters of the deformities are demonstrated here and specific historic features such as age of onset and mode of obstetric delivery are explored. The clinical significance and potential pathogenesis of this finding is unclear, though these cases are relevant in highlighting a novel presentation that we henceforth term focal idiopathic calvarial thinning.
颅骨局部变薄与潜在的系统性疾病无关并不常见。在医学文献中有记录的此类病例中，大多数是双侧顶骨变薄，这种情况往往发生在老年女性身上，导致颅骨双侧对称、规则形状的凹陷。作者描述了 2 例青少年男性单侧、局灶性、不规则形状的颅骨变薄，这些病例没有明显的诱发事件，也与系统性疾病、已知综合征或既往创伤无关。这里展示了畸形的性质和物理参数，并探讨了特定的病史特征，如发病年龄和分娩方式。这种发现的临床意义和潜在发病机制尚不清楚，但这些病例突显了一种新的表现形式，我们将其称为局灶性特发性颅骨变薄，因此具有重要意义。
