Suppr超能文献

患者个体化临床药学方案如何在矫形骨科护理途径中确保治疗护理(5P 项目)?

How a Patient Personalised Clinical Pharmacy Programme Can Secure Therapeutic Care in an Orthogeriatric Care Pathway (5P Project)?

机构信息

Pharmacie, Hospices Civils de Lyon, Lyon, France.

Pharmacie Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.

出版信息

Clin Interv Aging. 2021 Oct 21;16:1857-1867. doi: 10.2147/CIA.S325035. eCollection 2021.

Abstract

BACKGROUND

A new model was developed for integrating a personalised clinical pharmacy programme (5P project) into the orthogeriatric care pathway.

OBJECTIVE

To secure the therapeutic care of orthogeriatric patients.

DESIGN AND SETTING

Prospective descriptive study in a multisite teaching hospital from June 2019 to January 2020.

SUBJECTS

Patients aged ≥75 years admitted for hip fracture.

METHODS

A prescription review was performed for all patients at inclusion. Other clinical pharmacy activities (additional prescription review, pharmaceutical interviews, medication reconciliation) were dedicated to "high-risk" patients. Potential medication errors (ME), either pharmaceutical interventions (PI) or unintentional discrepancies (UID), were recorded. The potential clinical impact of PI was evaluated by a pluriprofessional expert panel using a validated tool.

RESULTS

In the 455 patients included, 955 potential ME were detected, that is ≥1 potential ME for 324/455 (71%) patients. In acute care, 561 PI were formulated during prescription review for 440/455 (97%) patients and 348/561 (62%) were accepted by physicians. Medication reconciliation was performed for 213 patients, 316 UID were identified. In rehabilitation units, a second prescription review was performed for 112/122 (92%) "high-risk" patients, leading to 61 PI. The clinical impact was evaluated for 519/622 (83%) PI. A consensus was obtained for 310/519 (60%) PI: 147/310 (47%) were rated as having minor clinical impact, 138/310 (45%) moderate, 22/310 (7%) major, 2/310 (0.6%) vital, and 1/310 (0.3%) null.

CONCLUSION

The 5P project secured the orthogeriatric care pathway by detecting a great number of potential ME, including PI mostly considered as having a significant clinical impact.

摘要

背景

开发了一种新模型,将个性化临床药学方案(5P 项目)整合到矫形骨科护理路径中。

目的

确保矫形科患者的治疗护理。

设计和设置

2019 年 6 月至 2020 年 1 月在多地点教学医院进行的前瞻性描述性研究。

受试者

年龄≥75 岁因髋部骨折入院的患者。

方法

对所有纳入患者进行处方审查。其他临床药学活动(额外的处方审查、药物学访谈、药物重整)专门针对“高危”患者。记录潜在药物错误(ME),包括药物干预(PI)或非故意差异(UID)。PI 的潜在临床影响由多专业专家小组使用经过验证的工具进行评估。

结果

在纳入的 455 名患者中,发现了 955 个潜在的 ME,即 324/455(71%)名患者有≥1 个潜在的 ME。在急性护理中,对 440/455(97%)名患者进行了处方审查,并提出了 561 项 PI,其中 348/561(62%)项被医生接受。对 213 名患者进行了药物重整,发现了 316 个 UID。在康复病房,对 122 名“高危”患者中的 112 名进行了第二次处方审查,提出了 61 项 PI。对 622 项 PI 中的 519 项(83%)进行了临床影响评估。对 310 项 PI 中的 310 项(60%)达成共识:147 项 PI(47%)被认为具有较小的临床影响,138 项 PI(45%)具有中等临床影响,22 项 PI(7%)具有较大临床影响,2 项 PI(0.6%)具有生命危险,1 项 PI(0.3%)无影响。

结论

5P 项目通过检测大量潜在 ME,包括被认为具有显著临床影响的 PI,从而确保了矫形科护理路径的安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d56/8544550/8fe0bdfa481b/CIA-16-1857-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验