Xu Hang, Zhu Sicheng, Zhang Wenhui, Ji Rong
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, Jiangsu, China.
Quanzhou Institute for Environmental Protection Industry, Nanjing University, Quanzhou 362000, Fujian, China.
Sheng Wu Gong Cheng Xue Bao. 2021 Oct 25;37(10):3459-3474. doi: 10.13345/j.cjb.210428.
Sulfonamides (SAs) are a kind of antibiotics widely used in medical treatment and livestock breeding. However, they have poor degradability in human and animal intestines, and will enter the sewage treatment system through the discharge of feces and urine. The aerobic activated sludge (AAS) in wastewater treatment plant was found to be able to effectively transform SAs. This article summarizes the advances in biodegradation of SAs in aerobic activated sludge system, which includes the biodegradation mechanisms, the main biodegradation pathways, and the environmental factors affecting the degradation efficiency. Challenges encountered in the current research were discussed, with the aim to provide scientific basis for optimizing the biodegradation of SAs in wastewater treatment process.
磺胺类药物（SAs）是一类广泛应用于医疗和家畜养殖的抗生素。然而，它们在人和动物肠道中的降解性较差，并会通过粪便和尿液排放进入污水处理系统。研究发现，污水处理厂的好氧活性污泥（AAS）能够有效转化磺胺类药物。本文综述了好氧活性污泥系统中磺胺类药物生物降解的研究进展，包括生物降解机制、主要生物降解途径以及影响降解效率的环境因素。讨论了当前研究中遇到的挑战，旨在为优化污水处理过程中磺胺类药物的生物降解提供科学依据。
