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[慢性淋巴细胞白血病]

[Chronic lymphocytic leukaemia].

作者信息

da Cunha-Bang Caspar, Brighel Christian, Niemann Carsten Utoft

出版信息

Ugeskr Laeger. 2021 Oct 18;183(42).

Abstract

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the world with approximately 450 new cases yearly in Denmark. The disease is highly heterogeneous, and half of the patients will never require treatment. The standard treatment is chemoimmunotherapy, but highly effective targeted therapies are approved for patients with high-risk disease or relapse as summarised in this review. The Danish CLL guidelines are continuously updated based on results from ongoing clinical trials and international guidelines.

摘要

慢性淋巴细胞白血病(CLL)是全球最常见的白血病,丹麦每年约有450例新发病例。该疾病具有高度异质性,半数患者无需治疗。标准治疗方法是化疗免疫疗法,但如本综述所述,高效靶向疗法已获批用于高危疾病或复发患者。丹麦CLL指南会根据正在进行的临床试验结果和国际指南不断更新。

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