Department of Internal Medicine, University of Iowa Hospital and Clinics, Iowa City, Iowa.
Department of Neurology, Mayo Clinic Health System, Eau Claire, Wisconsin,
WMJ. 2021 Oct;120(3):247-249.
The mediodorsal nucleus is a subcomponent of the thalamus hypothesized to have a role in memory pathways. Given the limited number of reported cases and associated images, its clinical significance has not yet been fully elucidated.
We report the case of a 53-year-old man who presented with verbal amnesia, including deficits of both recall and recognition. High-resolution magnetic resonance imaging demonstrated a well-defined infarct contained within the mediodorsal nucleus.
Current literature reports a range of conclusions regarding the extent to which the mediodorsal nucleus is involved in memory pathways. Several case series have attempted to localize infarcts by combining neuropsychology testing with imaging but were constrained by dated imaging modalities often dispersed with impurities.
Our case demonstrates that isolated lesions of the mediodorsal nucleus can lead to deficits in both recall and recognition and that high-resolution magnetic resonance imaging is necessary when a thalamic infarct is suspected.
内侧背核是丘脑的一个亚核团，据推测在记忆通路上具有作用。鉴于报告的病例数量有限且相关图像较少，其临床意义尚未完全阐明。
我们报告了一例 53 岁男性患者，表现为言语性遗忘，包括回忆和识别缺陷。高分辨率磁共振成像显示在 Mediodorsal 核内有一个界限清楚的梗死灶。
目前的文献报告了一系列关于 Mediodorsal 核在记忆通路上的参与程度的结论。有几项病例系列研究试图通过将神经心理学测试与影像学相结合来定位梗死灶，但由于成像方式陈旧且常伴有杂质而受到限制。
我们的病例表明，Mediodorsal 核的孤立性病变可导致回忆和识别缺陷，当怀疑有丘脑梗死时，需要进行高分辨率磁共振成像。
