Suppr超能文献

[不同发育水平自闭症谱系障碍儿童的语言分析]

[Analysis of language of children with autism spectrum disorder at different developmental levels].

作者信息

Wei Q H, Zhang Y, He Y, Mu Y, Cheng Q

机构信息

Department of Child Healthcare, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.

出版信息

Zhonghua Er Ke Za Zhi. 2021 Nov 2;59(11):922-927. doi: 10.3760/cma.j.cn112140-20210309-00193.

Abstract

To explore the language characteristics of children with autism spectrum disorder (ASD) at different developmental levels. The clinical data of 103 children with ASD who attended the Children's Hospital of Chongqing Medical University from January 2018 to December 2020 was analyzed retrospectively. They were divided into typical development and abnormal development (including mild and moderate or severe) groups based on developmental diagnostic scale results, and also devided into 2-3, 4-6, and 7-8 years of age groups based on age. The language characteristics of children with ASD at different developmental levels and different ages were compared by Pearson's chi-square or Fisher's exact probabilty test, test, analysis of variance, or Kruskal-Wallis test. The relationship between language ability and core symptoms of ASD was analyzed by Pearson correlation test. Among 103 children with ASD, 86 were males and 17 were females, with an age of (5.5±1.5) years. A total of 61 children were charactered as typical development and 42 as abnormal (32 mild and 10 moderate or severe). There were no significant differences in developmental scale, overall language, receptive, expressive, syntax, and semantics scores among the three different age groups (all >0.05). The detection rate of abnormal language ability in the typical development group was significantly lower than that in the abnormal development group (49.2% (30/61) 100.0% (42/42), <0.01). Receptive, expressive, semantics, and syntax scores of the typical development groups were significantly higher than those of the mildly and moderately or severely abnormal group (89±13 76±11 71±8, =18.61, <0.01; 80±12 66±8 58±7, =29.69, <0.01; 92±14 78±14 71±11, =17.26, <0.01; 83±10 71±8 64±5, =29.35, <0.01). Within the abnormal development group, there were no significant correlations between language ability and the core symptoms of ASD (=-0.02-0.58, all >0.05). Within the typical development group, there were no significant correlations between language ability and social interaction, repetitive stereotypes, and limited interests (=0--0.22, all >0.05). However, overall language, receptive, semantics, and expressive language abilities were negatively correlated with communication (=-0.28--0.36, all <0.05), and there was no significant correlation between syntax and communication (=-0.24, >0.05) in typical developmental group. The majority of children with ASD manifest language development disorders, mainly in the aspects of expressive and syntax language. Children with ASD with more delayed developmental level have more severe language disorder. About half children with ASD with normal development have language development disorders. The language ability of children with ASD is minimally correlated with ASD core symptoms.

摘要

探讨不同发育水平的自闭症谱系障碍(ASD)儿童的语言特征。回顾性分析2018年1月至2020年12月在重庆医科大学附属儿童医院就诊的103例ASD儿童的临床资料。根据发育诊断量表结果将其分为典型发育组和异常发育组(包括轻度、中度或重度),并根据年龄分为2 - 3岁、4 - 6岁和7 - 8岁组。采用Pearson卡方检验、Fisher确切概率检验、方差分析或Kruskal - Wallis检验比较不同发育水平和不同年龄的ASD儿童的语言特征。采用Pearson相关检验分析语言能力与ASD核心症状之间的关系。103例ASD儿童中,男86例,女17例,年龄为(5.5±1.5)岁。共有61例儿童为典型发育,42例为异常发育(32例轻度,10例中度或重度)。三个不同年龄组在发育量表、总体语言、接受性、表达性、句法和语义得分方面均无显著差异(均>0.05)。典型发育组语言能力异常检出率显著低于异常发育组(49.2%(30/61)对100.0%(42/42),<0.01)。典型发育组的接受性、表达性、语义和句法得分显著高于轻度、中度或重度异常组(89±l3对76±l1、71±8,F = 18.61,<0.01;80±12对66±8、58±7,F = 29.69,<0.01;92±14对78±l4、71±11,F = 17.26,<0.01;83±10对71±8、64±5,F = 29.35,<0.01)。在异常发育组中,语言能力与ASD核心症状之间无显著相关性(r = - 0.02 - 0.58,均>0.05)。在典型发育组中,语言能力与社会交往、重复刻板行为和兴趣局限之间无显著相关性(r = 0 - - 0.22,均>0.05)。然而,典型发育组的总体语言、接受性、语义和表达性语言能力与沟通呈负相关(r = - 0.28 - - 0.36,均<0.05),句法与沟通之间无显著相关性(r = - 0.24,>0.05)。大多数ASD儿童存在语言发育障碍,主要表现在表达性和句法语言方面。发育水平延迟越明显的ASD儿童语言障碍越严重。约一半发育正常的ASD儿童存在语言发育障碍。ASD儿童语言能力与ASD核心症状的相关性最小。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验