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后路减压手术治疗腰椎管狭窄症时应保留后正中结构吗?:系统评价和荟萃分析。

Should Posterior Midline Structures Be Preserved in Decompression Surgery for Lumbar Spinal Stenosis?: A Systematic Review and Meta-analysis.

机构信息

Department of Orthopaedic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, China.

出版信息

Clin Spine Surg. 2022 Oct 1;35(8):341-349. doi: 10.1097/BSD.0000000000001268. Epub 2021 Oct 28.

Abstract

STUDY DESIGN

This was a systematic review and meta-analysis study.

OBJECTIVE

The purpose of this study is to evaluate the available evidence on the preservation of posterior midline structures in decompression surgery for lumbar spinal stenosis (LSS).

SUMMARY OF BACKGROUND DATA

The gold-standard treatment for LSS refractory to conservative management is facet-preserving laminectomy. The question remains whether the midline structures should be preserved in decompression surgery for LSS.

MATERIALS AND METHODS

We performed a systematic review of the Medline, PubMed, Embase, and Cochrane databases in search of published reports comparing midline structure preservation (MSP) and conventional laminectomy (CL) for LSS. The population was divided into 2 groups: (1) MSP group (intervention) and (2) CL group (control). The various outcome parameters including blood loss, operation time, hospital stay, back and leg pain, functional scores including Oswestry Disability Index (ODI) score, Japanese Orthopedic Association score, and 36-Item Short Form Survey (SF-36) scores, satisfaction, and instability rates were analyzed. Data were extracted and aggregated for meta-analysis.

RESULTS

Of the published reports, 16 met our inclusion criteria with an aggregated 540 in the intervention and 538 in the control groups, respectively. The aggregated data demonstrated patients undergoing MSP had significantly decreased back pain Visual Analog Scale compared with CL, regardless of time after surgery ( P =0.007). The MSP group also showed a significantly lower Oswestry Disability Index score and SF-36 Mental Component Summary score ( P =0.005 and 0.03, respectively) and longer 6-month walking distance ( P <0.00001). The patient satisfaction rate was significantly higher in the MSP group ( P =0.02), and the instability rate was significantly lower in the MSP group compared with the CL group ( P <0.0001). At 3 days after surgery, MSP significantly decreased the level of creatinine phosphokinase ( P <0.00001). Regarding intraoperative blood loss, hospital stay, leg pain Visual Analog Scale score, Japanese Orthopedic Association score, and SF-36 Physical Component Summary score, there were no significant differences between the 2 groups. However, MSP showed significantly higher operation time ( P =0.04).

CONCLUSIONS

We concluded despite heterogenous and limited data, this study suggests that preservation of midline structure leads to less severe back pain, better functional recovery, and satisfaction rate. Meanwhile, it decreases creatinine phosphokinase level and instability rate.

LEVEL OF EVIDENCE

Level III-therapeutic.

摘要

研究设计

这是一项系统评价和荟萃分析研究。

目的

本研究旨在评估腰椎管狭窄症(LSS)减压术中保留后正中线结构的现有证据。

背景资料概要

对保守治疗无效的 LSS 的金标准治疗是保留关节突的椎板切除术。问题仍然是在 LSS 的减压术中是否应该保留中线结构。

材料和方法

我们对 Medline、PubMed、Embase 和 Cochrane 数据库进行了系统检索,以寻找比较保留中线结构(MSP)和传统椎板切除术(CL)治疗 LSS 的已发表报告。人群分为 2 组:(1)MSP 组(干预组)和(2)CL 组(对照组)。分析了各种结局参数,包括出血量、手术时间、住院时间、腰背腿痛、功能评分,包括 Oswestry 残疾指数(ODI)评分、日本矫形协会评分和 36 项简短健康调查(SF-36)评分、满意度和不稳定性发生率。提取数据并进行荟萃分析。

结果

在已发表的报告中,有 16 项符合我们的纳入标准,干预组有 540 项,对照组有 538 项。汇总数据显示,接受 MSP 的患者与接受 CL 的患者相比,腰背疼痛视觉模拟量表明显降低,无论手术后时间如何(P =0.007)。MSP 组的 Oswestry 残疾指数评分和 SF-36 心理成分综合评分也明显较低(P =0.005 和 0.03),6 个月的步行距离也更长(P <0.00001)。MSP 组的患者满意度明显更高(P =0.02),MSP 组的不稳定性发生率明显低于 CL 组(P <0.0001)。术后 3 天,MSP 明显降低了肌酸磷酸激酶水平(P <0.00001)。关于术中出血量、住院时间、腿痛视觉模拟量表评分、日本矫形协会评分和 SF-36 生理成分综合评分,两组间无显著性差异。然而,MSP 的手术时间明显更长(P =0.04)。

结论

尽管数据存在异质性和局限性,但本研究表明,保留中线结构可导致更轻的腰背疼痛、更好的功能恢复和更高的满意度。同时,它降低了肌酸磷酸激酶水平和不稳定性发生率。

证据水平

三级-治疗。

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