Mohammadmirzaei Zahra, Farahmand Habib, Ahmadi Jafar, Rezvan Sajad, Noori Enayatollah, Hormati Ahmad
Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Department of Radiology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Middle East J Dig Dis. 2021 Apr;13(2):103-108. doi: 10.34172/mejdd.2021.212. Epub 2021 May 29.
BACKGROUND Metabolic syndrome can be considered as a combination of metabolic disorders that may led to an increased risk of some diseases such type II diabetes, cardiovascular diseases, myocardial infarction, and is the cause of mortality from coronary artery disease. Its prevalence is particularly high in women. There is evidence that pancreatic fat, as a key factor in non-alcoholic fatty liver and metabolic syndrome, numerates as an early indicator of abnormal fat deposition. METHODS In this study, we enrolled 262 patients, who were admitted to Ali Ibn Abi Talib Hospital in Rafsanjan city, using the non-random-sequential method. Data collection tools were a questionnaire containing demographic characteristics (age, sex, history of diseases, etc.) and a checklist including MetS (based on NCEP/ATP III criteria and Diabetes Committee), pancreatic density (P), and spleen (S) and pancreatic index (P/S). One-way ANOVA and Post-Hoc and Chi-square tests were used for statically analyses. RESULTS The prevalence of metabolic syndrome was 34.8%, index of pancreas in the group without and with metabolic syndrome were 0.85 ± 0.11 and 0.74 ± 0.29 Hounsfield Units, respectively. CONCLUSION Compared with the group with at least one criterion and the group with the complete criteria ( = 0.013), pancreas index was higher in the group without metabolic syndrome.
代谢综合征可被视为多种代谢紊乱的组合,这可能会增加患某些疾病的风险,如2型糖尿病、心血管疾病、心肌梗死,并且是冠状动脉疾病致死的原因。其在女性中的患病率尤其高。有证据表明,胰腺脂肪作为非酒精性脂肪肝和代谢综合征的关键因素,是脂肪异常沉积的早期指标。
在本研究中,我们采用非随机序贯法招募了262名入住拉夫桑詹市阿里·伊本·阿比·塔利卜医院的患者。数据收集工具包括一份包含人口统计学特征(年龄、性别、疾病史等)的问卷,以及一份清单,其中包括代谢综合征(基于美国国家胆固醇教育计划成人治疗组第三次报告标准和糖尿病委员会标准)、胰腺密度(P)、脾脏(S)和胰腺指数(P/S)。采用单因素方差分析、事后检验和卡方检验进行统计学分析。
代谢综合征的患病率为34.8%,无代谢综合征组和有代谢综合征组的胰腺指数分别为0.85±0.11和0.74±0.29亨氏单位。
与至少有一项标准的组和具有完整标准的组相比(P = 0.013),无代谢综合征组的胰腺指数更高。