Adegbola Samuel O, Sahnan Kapil, Twum-Barima Charlene, Iqbal Nusrat, Reza Lillian, Lung Phillip, Warusavitarne Janindra, Tozer Phil, Hart Ailsa
St Mark's Hospital and Academic Institute, Harrow, UK.
Department of Surgery and Cancer, Imperial College London, London, UK.
Frontline Gastroenterol. 2020 Aug 13;12(6):515-523. doi: 10.1136/flgastro-2020-101489. eCollection 2021.
Perianal manifestations of Crohn's disease constitute a distinct disease phenotype commonly affecting patients and conferring an increased risk of disability and disease burden. Much research has gone into management of fistulising manifestations, with biological therapy changing the landscape of treatment. In this article, we discuss the up-to-date surgical and medical management of perianal fistulas, highlighting current consensus management guidelines and the evidence behind them, as well as future directions in management.
克罗恩病的肛周表现构成一种独特的疾病表型，常影响患者，并增加致残风险和疾病负担。针对瘘管形成表现的管理已开展了大量研究，生物疗法改变了治疗格局。在本文中，我们讨论肛周瘘管最新的手术和药物管理方法，重点介绍当前的共识管理指南及其背后的证据，以及管理的未来方向。
