Wei Nancy, Wong Vincent, Matz Ariana, Vemulakonda Lakshmisree Akhila, Wang Xiaotong, Phillips John
New York Medical College, Valhalla, NY, USA.
Department of Urology, New York Medical College, Valhalla, NY, USA.
Urol Case Rep. 2021 Oct 14;40:101900. doi: 10.1016/j.eucr.2021.101900. eCollection 2022 Jan.
Hepatocellular carcinoma (HCC) arises from several different etiologies and carries a poor prognosis. Extrahepatic metastases of HCC are most frequently found in the lungs, lymph nodes, and bones, with adrenal metastases reported in less than 15% of metastatic cases. Herein, we report a case of a 71-year-old man without prior liver disease who presented with a 9-cm right adrenal mass extending into the IVC consistent with HCC on subsequent surgical pathology and immunohistochemical staining. Etiological possibilities for an adrenal tumor as the first presentation of HCC include metastasis from occult primary liver HCC, intra-adrenal hepatic heterotopia, and adrenohepatic fusion.
肝细胞癌(HCC)由多种不同病因引起,预后较差。HCC的肝外转移最常见于肺、淋巴结和骨骼,肾上腺转移在转移性病例中报告少于15%。在此,我们报告一例71岁男性,既往无肝脏疾病,出现一个9厘米的右肾上腺肿块,延伸至下腔静脉,后续手术病理和免疫组化染色证实为HCC。肾上腺肿瘤作为HCC首发表现的病因可能性包括隐匿性原发性肝HCC转移、肾上腺内肝异位和肾上腺肝融合。