Hussain Muzna, Hanna Mazen, Jaber Wael, Collier Patrick
Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
CASE (Phila). 2021 Aug 18;5(5):313-317. doi: 10.1016/j.case.2021.07.010. eCollection 2021 Oct.
• We present an atypical variant case of wild-type transthyretin cardiac amyloidosis. • Amyloid deposition occurred mainly in the interventricular septum. • The classic apical sparing pattern was absent, despite other suggestive findings. • A high index of suspicion for amyloid should still be sought in such cases. • Multimodality imaging should be considered to investigate variant amyloid forms.
• 我们报告了一例野生型转甲状腺素蛋白心脏淀粉样变性的非典型变异病例。
• 淀粉样沉积主要发生在室间隔。
• 尽管有其他提示性发现,但经典的心尖 sparing 模式不存在。
• 在此类病例中仍应高度怀疑淀粉样变性。
• 应考虑采用多模态成像来研究变异型淀粉样蛋白形式。