O'Brien Michael C, Dzieza Wojciech K, Bruner Michelle L, Farmer Kevin W
University of Florida College of Medicine, Gainesville, Florida, U.S.A.
Department of Orthopaedics and Rehabilitation, University of Florida, Gainesville, Florida, U.S.A.
Arthrosc Sports Med Rehabil. 2021 Jul 24;3(5):e1315-e1320. doi: 10.1016/j.asmr.2021.05.012. eCollection 2021 Oct.
To assess the quantity of morselized cartilage that can be harvested from the non-load-bearing portion of the talus for immediate reimplantation.
Non-load-bearing talar cartilage was harvested from 5 cadaveric specimens using a standard arthroscopic approach. Cartilage was separated from the talus in maximum dorsiflexion at the junction of the talar head and neck, grasped, and morselized into a graft using a cartilage particulator. The volume of reclaimed cartilage was measured, and the extrapolated area of coverage was compared to average osteochondral lesions of the talus previously reported.
The total yield of cartilage graft following processing that was obtained from 5 ankle joints ranged from 0.3 mL to 2.1 mL with a mean volume of 1.3 ± 0.7 mL, yielding a theoretical 13.2 ± 7.1 cm coverage with a 1-mm monolayer. While the average size of osteochondral lesions of the talus is difficult to estimate, they may range from 0.5 cm to 3.7 cm according to the literature.
This study validated that it is possible to harvest sufficient amount of cartilage for an autologous morselized cartilage graft via a single-stage, single-site surgical and processing technique to address most talar articular cartilage defects.
Particulated cartilage autografts have shown promise in surgical management of cartilage defects. A single-site, single-staged procedure that uses a patient's autologous talar cartilage from the same joint has the potential to reduce morbidity associated with multiple surgical sites, multistaged procedure, or nonautologous tissue in ankle surgery.
评估可从距骨非负重部位获取用于即刻再植入的碎骨软骨的量。
采用标准关节镜入路从5个尸体标本中获取距骨非负重软骨。在距骨头与颈的交界处最大背屈位将软骨与距骨分离,抓取后使用软骨微粒化器将其制成移植物。测量回收软骨的体积,并将推算的覆盖面积与先前报道的距骨平均骨软骨损伤面积进行比较。
从5个踝关节获取的经处理后的软骨移植物总产量为0.3 mL至2.1 mL,平均体积为1.3±0.7 mL,理论上1毫米单层覆盖面积为13.2±7.1平方厘米。虽然距骨骨软骨损伤的平均大小难以估计,但根据文献,其范围可能为0.5厘米至3.7厘米。
本研究证实,通过单阶段、单部位手术及处理技术获取足够量的软骨用于自体碎骨软骨移植以解决大多数距骨关节软骨缺损是可行的。
颗粒状软骨自体移植在软骨缺损的手术治疗中已显示出前景。在踝关节手术中,采用单部位、单阶段手术,使用患者同一关节的自体距骨软骨,有可能降低与多个手术部位、多阶段手术或非自体组织相关的发病率。