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截至 2021 年 9 月 28 日，法国发生大规模手足口病疫情。

A large-scale outbreak of hand, foot and mouth disease, France, as at 28 September 2021.

机构信息

CHU Clermont-Ferrand, Laboratoire de Virologie, Centre National de Référence des entérovirus et parechovirus - Laboratoire Associé, Clermont-Ferrand, France.

Université d'Auvergne, LMGE UMR CNRS 6023 Equipe EPIE - Epidémiologie et physiopathologie des infections à entérovirus, Faculté de Médecine, Clermont-Ferrand, France.

出版信息

Euro Surveill. 2021 Oct;26(43). doi: 10.2807/1560-7917.ES.2021.26.43.2100978.

DOI:10.2807/1560-7917.ES.2021.26.43.2100978
PMID:34713796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8555367/
Abstract

We report a large-scale outbreak of hand, foot and mouth disease (HFMD) in France. As at 28 September 2021, 3,403 cases have been reported (47% higher than in 2018-19). We prospectively analysed 210 clinical samples; 190 (90.5%) were enterovirus-positive. Most children presented with atypical HFMD. Coxsackievirus (CV)A6 (49.5%; 94/190) was predominant; no enterovirus A71 was detected. Dermatological and neurological complications of HFMD justify prospective syndromic and virological surveillance for early detection of HFMD outbreaks and identification of associated types.

摘要

我们报告了法国的一次大规模手足口病（HFMD）暴发。截至 2021 年 9 月 28 日，共报告了 3403 例病例（比 2018-19 年增加了 47%）。我们前瞻性分析了 210 份临床样本；190 份（90.5%）为肠道病毒阳性。大多数患儿表现为非典型手足口病。柯萨奇病毒 A6（49.5%；94/190）占主导地位；未检测到肠道病毒 A71。手足口病的皮肤和神经并发症表明，需要进行前瞻性综合征和病毒学监测，以便早期发现手足口病暴发并识别相关类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/473feeb2a107/2100978-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/272eb8e4be4e/2100978-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/7fbe0813cb8a/2100978-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/832cd5639bb2/2100978-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/473feeb2a107/2100978-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/272eb8e4be4e/2100978-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/7fbe0813cb8a/2100978-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/832cd5639bb2/2100978-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8c/8555367/473feeb2a107/2100978-f4.jpg

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