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不同的断点解释对临床意义重大的厌氧菌对莫西沙星的耐药率产生了显著影响。

Different breakpoints interpretation yielded distinct resistance rates to moxifloxacin of clinically significant anaerobic bacteria.

机构信息

Department of Microbiology and Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital Virgen de las Nieves, Granada, Spain.

Department of Pharmacy, University Hospital Virgen de las Nieves, Granada, Spain.

出版信息

Anaerobe. 2021 Dec;72:102471. doi: 10.1016/j.anaerobe.2021.102471. Epub 2021 Oct 28.

DOI:10.1016/j.anaerobe.2021.102471
PMID:34715325
Abstract

The aim of this study was to describe the differences in antimicrobial susceptibility to moxifloxacin between European Committee on Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI) in anaerobic microorganisms. Overall, resistance to moxifloxacin appears to be high in almost all groups of anaerobes, but enormous differences in susceptibility rates between these two committees could be observed.

摘要

本研究旨在描述欧洲抗菌药物敏感性测试委员会（EUCAST）和临床与实验室标准协会（CLSI）在厌氧微生物中对莫西沙星的药敏差异。总体而言，几乎所有厌氧菌群对莫西沙星的耐药率都很高，但这两个委员会之间的药敏率存在巨大差异。

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