Xiangya School of Nursing, Central South University, Changsha, Hunan, China.
School of Health, Federation University Australia, Melbourne, Victoria, Australia.
BMJ Open. 2021 Oct 29;11(10):e053634. doi: 10.1136/bmjopen-2021-053634.
To explore willingness and preferred ways to use HIV pre-exposure prophylaxis (PrEP), factors associated with willingness, and potential barriers to PrEP use among men who have sex with men (MSM) in Changsha, China.
A cross-sectional survey was conducted from 25 June to 31 August 2019. Two hundred and fifty-five MSM were recruited from three community-based organisations (CBOs) in Changsha City. Willingness and potential barriers to use PrEP were examined using researcher-created scales. Univariate and multivariate logistic regression was used to analyse the factors associated with willingness to use PrEP. P values <0.05 were considered significant.
Three MSM inclusive CBOs in Changsha, Hunan Province, China.
255 HIV-negative MSM were recruited through their CBOs with snowball sampling.
Less than half of the participants (43.1%) had heard of PrEP and 15.3% were willing to use PrEP. The participants reported higher willingness to use event-driven PrEP (3.70±0.07) than daily PrEP (2.65±0.07). Higher self-rated risk and fear of contracting HIV (OR: 14.47, 95% CI 2.19 to 95.53), awareness of PrEP (OR: 4.20, 95% CI 1.64 to 10.73), sharing one's own sexual orientation with parents or siblings (OR: 2.52, 95% CI 1.54 to 7.20) and having a university education or above (OR:0.29, 95% CI 0.12 to 0.72) were associated with willingness to use PrEP. Only 12.2% of the sample was concerned about potential barriers to PrEP use.
Efforts to improve awareness and knowledge of PrEP, teach self-evaluation of HIV infection risk and provide social and emotional support for MSM are needed to scale up PrEP implementation in China.
探索中国长沙市男男性行为者(MSM)使用 HIV 暴露前预防(PrEP)的意愿和偏好方式、与使用意愿相关的因素,以及 PrEP 使用的潜在障碍。
2019 年 6 月 25 日至 8 月 31 日进行了一项横断面调查。从长沙市三个社区组织(CBO)招募了 255 名 MSM。使用研究人员创建的量表评估使用 PrEP 的意愿和潜在障碍。使用单变量和多变量逻辑回归分析与使用 PrEP 意愿相关的因素。P 值<0.05 被认为具有统计学意义。
中国湖南省长沙市三个 MSM 包容性 CBO。
通过 CBO 采用雪球抽样法招募了 255 名 HIV 阴性 MSM。
不到一半的参与者(43.1%)听说过 PrEP,15.3%表示愿意使用 PrEP。参与者报告称,他们更愿意使用事件驱动型 PrEP(3.70±0.07),而不是每日 PrEP(2.65±0.07)。更高的自我评估风险和担心感染 HIV(OR:14.47,95%CI 2.19 至 95.53)、对 PrEP 的认识(OR:4.20,95%CI 1.64 至 10.73)、与父母或兄弟姐妹分享自己的性取向(OR:2.52,95%CI 1.54 至 7.20)和拥有大学学历或以上(OR:0.29,95%CI 0.12 至 0.72)与使用 PrEP 的意愿相关。只有 12.2%的样本对 PrEP 使用的潜在障碍表示担忧。
需要努力提高 MSM 对 PrEP 的认识和了解,教授 HIV 感染风险的自我评估,并为 MSM 提供社会和情感支持,以扩大中国 PrEP 的实施。