Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Pathology, The University of Texas Medical Branch, Galveston, TX, USA.
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ann Diagn Pathol. 2022 Feb;56:151841. doi: 10.1016/j.anndiagpath.2021.151841. Epub 2021 Oct 23.
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a low-grade B cell lymphoma that can affect any organ, usually preceded by acquisition of MALT in response to antigenic stimulus provided by infections or autoimmune diseases. Most often, MALT lymphoma involves the stomach (about 35% of cases), followed by the ocular adnexal region, skin, lungs, and salivary glands, but virtually any extranodal site can be involved. MALT lymphomas are less common at sites of normal MALT tissue, such as Waldeyer ring and the ileocecal region of the gastrointestinal tract. Lymphomas involving the tongue are extremely rare and represent approximately 3% of all lymphomas involving the head and neck region. In this study, we discuss potentially challenging diagnostic aspects of MALT lymphoma involving the tongue and review and summarize the available literature about this topic.
黏膜相关淋巴组织（MALT）结外边缘区淋巴瘤（MALT 淋巴瘤）是一种低级别 B 细胞淋巴瘤，可影响任何器官，通常在获得 MALT 后发生，这是对感染或自身免疫性疾病提供的抗原刺激的反应。大多数情况下，MALT 淋巴瘤累及胃（约 35%的病例），其次是眼附属器区域、皮肤、肺和唾液腺，但实际上任何结外部位都可能受累。MALT 淋巴瘤在正常 MALT 组织部位较少见，如瓦尔德耶尔环和胃肠道的回盲部。累及舌的淋巴瘤极为罕见，约占头颈部所有淋巴瘤的 3%。在本研究中，我们讨论了累及舌的 MALT 淋巴瘤的一些具有挑战性的诊断方面，并回顾和总结了这一主题的现有文献。
