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前列腺素F2α给药对母羊早期妊娠的影响。

Effect of prostaglandin F2 alpha administration on early pregnancy in ewes.

作者信息

Naasz P E, Slyter A L

出版信息

J Anim Sci. 1987 Apr;64(4):1127-33. doi: 10.2527/jas1987.6441127x.

DOI:10.2527/jas1987.6441127x
PMID:3471747
Abstract

Two trials were conducted with ewes to determine the effects of prostaglandin F2 alpha (PGF) administration during the first week of gestation. In trial 1, ewes (n = 134) were checked for breeding activity once daily and half of them received 10 mg PGF im at either 0, 24, 48, 72, 96, 120 or 144 h after detection of a breeding mark. The other half served as uninjected controls. In trial 2, ewes (n = 153) were checked for breeding activity twice daily. Two-thirds of the ewes received 10 mg PGF at either 24, 36, 48, 60, 72, 84, 96, 108, 120 and 132 h following detection of a breeding mark. The other one-third of the ewes served as uninjected controls corresponding to treatment times of 24, 48, 72, 96 or 120 h. In trial 1, the percentage of ewes lambing as a result of first service decreased as time of administration of PGF increased. The first-service pregnancy rate was 87.5% for ewes given PGF at 0 h and 0% for ewes given PGF at 144 h. Fewer (P less than .05) ewes given PGF at 96, 120 or 144 h after first mating lambed than control ewes. Similarly in trial 2, fewer (P less than .05) ewes given PGF at 96, 108, 120 or 132 h after first mating lambed than did controls. The total number of ewes lambing as a result of the entire breeding season did not differ (P greater than .05) between treated and control ewes in trial 1 (88.2 vs 87.3%) or trial 2 (85.7 vs 83.3%).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

进行了两项试验,以确定在妊娠第一周给母羊注射前列腺素F2α(PGF)的效果。在试验1中,每天检查一次母羊(n = 134)的繁殖活动,其中一半母羊在检测到配种标记后的0、24、48、72、96、120或144小时接受10毫克PGF肌肉注射。另一半作为未注射的对照。在试验2中,每天检查两次母羊(n = 153)的繁殖活动。三分之二的母羊在检测到配种标记后的24、36、48、60、72、84、96、108、120和132小时接受10毫克PGF。另外三分之一的母羊作为未注射的对照,对应于24、48、72、96或120小时的处理时间。在试验1中,由于首次配种而产羔的母羊百分比随着PGF给药时间的增加而降低。在0小时接受PGF的母羊首次配种妊娠率为87.5%,在144小时接受PGF的母羊为0%。在首次配种后96、120或144小时接受PGF的母羊产羔数少于对照母羊(P小于0.05)。同样在试验2中,在首次配种后96、108、120或132小时接受PGF的母羊产羔数少于对照母羊(P小于0.05)。在试验1(88.2%对87.3%)或试验2(85.7%对83.3%)中,经处理的母羊和对照母羊在整个繁殖季节产羔的总数没有差异(P大于0.05)。(摘要截短为250字)

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