FSBI "National Health and Research Center of Preventive Healthcare" of the Ministry of Health of Russia, Moscow, Russia.
FSBI SRC RF "Institute of Biomedical Problems" RAS, Moscow, Russia.
Clin Hemorheol Microcirc. 2022;80(4):373-387. doi: 10.3233/CH-211292.
To investigate structural and functional features of cutaneous microvasculature in men of working age with newly diagnosed arterial hypertension (AH).
The study included 161 apparently healthy men from 30 to 60 years, who underwent a comprehensive examination of cardiovascular system "from the heart to the capillaries". Control group (CG) included 60 normotensive men. AH group included 101 men with elevated BP.
There is no rarefaction of the capillary bed and latent fluid retention in the interstitial space in the skin in men with AH. No data were obtained for increased endothelial, neurogenic and myogenic tone of resistive cutaneous precapillary arterioles in AH group, but a decrease in the perfusion efficiency of the endothelial and myogenic mechanisms of tissue perfusion modulation was noted.
Obtained results allow making the assumption that metabolic disorders at the level of capillaries that are of a systemic nature prevail in men with the onset of AH.
研究新诊断为动脉高血压（AH）的工作年龄男性皮肤微血管的结构和功能特征。
本研究纳入了 161 名年龄在 30 至 60 岁之间的健康男性，他们接受了心血管系统的全面检查“从心脏到毛细血管”。对照组（CG）包括 60 名血压正常的男性。AH 组包括 101 名血压升高的男性。
在 AH 男性中，毛细血管床没有稀疏，间质中也没有潜在的液体潴留。AH 组中没有得到阻力性皮肤小动脉内皮、神经源性和肌源性张力增加的数据，但注意到内皮和肌源性组织灌注调节机制的灌注效率下降。
研究结果表明，在 AH 男性中，毛细血管水平的代谢紊乱占主导地位，且具有全身性。
