十二指肠壶腹肿瘤伴乳头状息肉恶变：病例报告及文献复习。

Department of Gastroenterology, Shidong Hospital of Shanghai, Shanghai 200433, People's Republic of China.

Department of Gastroenterology, 12476Tongji University, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, People's Republic of China.

J Int Med Res. 2021 Oct;49(10):3000605211053230. doi: 10.1177/03000605211053230.

Periampullary carcinoma refers to a malignant tumor within 2 cm of the duodenal ampulla. Primary ampullary carcinoma is very rare, accounting for only 0.2% of malignant gastrointestinal tumors. The small intestine accounts for 75% of the length of the gastrointestinal tract, and primary tumors in the small intestine account for only 2% of all gastrointestinal tumors. Here, we report the case of a duodenal ampullary tumor with malignant transformation of parapapillary polyps. The patient had both a primary ampullary tumor and high-grade intraepithelial neoplasia of juxtapapillary adenomatous duodenal polyps.

壶腹周围癌是指位于十二指肠乳头 2cm 以内的恶性肿瘤。原发性壶腹周围癌非常罕见，仅占恶性胃肠道肿瘤的 0.2%。小肠占胃肠道长度的 75%，而小肠原发性肿瘤仅占所有胃肠道肿瘤的 2%。在这里，我们报告了一例十二指肠壶腹肿瘤伴胰胆管合流异常处黏膜下腺瘤恶变。该患者既有原发性壶腹肿瘤，又有毗邻胰胆管合流异常处腺瘤性十二指肠黏膜高级别上皮内瘤变。