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聚苯乙烯磺酸钠诱导的胃壁积气：一种罕见的副作用。

Sodium Polystyrene Sulfonate-Induced Gastric Pneumatosis: A Rare Side Effect.

作者信息

Dasu Neethi, Khalid Yaser, Dasu Kirti, Joo Lucy, Blair Brian

机构信息

Department of Gastroenterology, Jefferson Health New Jersey, Cherry Hill, New Jersey, USA.

Department of Cardiology, The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA.

出版信息

Case Rep Gastroenterol. 2021 Sep 30;15(3):885-890. doi: 10.1159/000518929. eCollection 2021 Sep-Dec.

DOI:10.1159/000518929
PMID:34720839
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8543344/
Abstract

Kayexalate has been used in the USA since 1975 for the treatment of hyperkalemia. Prior case reports have shown that sorbitol added to kayexalate has been known to cause rare side effects of colonic necrosis. We present a unique case report of gastric pneumatosis as a complication of kayexalate.

摘要

自1975年以来，聚苯乙烯磺酸钠在美国一直用于治疗高钾血症。先前的病例报告显示，已知添加到聚苯乙烯磺酸钠中的山梨醇会引起罕见的结肠坏死副作用。我们报告一例独特的病例，胃积气是聚苯乙烯磺酸钠治疗的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/5e8805c5eac1/crg-0015-0885-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/1ea28cbce14d/crg-0015-0885-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/0ae03fc39ee4/crg-0015-0885-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/141bb80a044a/crg-0015-0885-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/5e8805c5eac1/crg-0015-0885-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/1ea28cbce14d/crg-0015-0885-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/0ae03fc39ee4/crg-0015-0885-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/141bb80a044a/crg-0015-0885-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5646/8543344/5e8805c5eac1/crg-0015-0885-g04.jpg

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Am J Surg Pathol. 2001 May;25(5):637-44. doi: 10.1097/00000478-200105000-00011.
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Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: case report and literature review.口服 Kayexalate 在山梨醇中致年轻患者结肠坏死：病例报告及文献复习。
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引用本文的文献

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Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies.非透析慢性肾脏病伴高钾血症患者的研究进展：结局与治疗策略。
Medicina (Kaunas). 2023 Feb 13;59(2):353. doi: 10.3390/medicina59020353.

本文引用的文献

1
Intestinal necrosis after co-administration of sodium polystyrene sulfonate and activated charcoal.聚苯乙烯磺酸钠与活性炭联合使用后发生肠坏死。
Clin Case Rep. 2020 Mar 12;8(4):722-724. doi: 10.1002/ccr3.2695. eCollection 2020 Apr.
2
Sodium polystyrene sulfonate crystals in the gastric wall of a patient with upper gastrointestinal bleeding and gastric perforation: an incidental finding or a pathogenic factor?上消化道出血和胃穿孔患者胃壁中的聚苯乙烯磺酸钠晶体：偶然发现还是致病因素？
J Surg Case Rep. 2018 Jun 13;2018(6):rjy138. doi: 10.1093/jscr/rjy138. eCollection 2018 Jun.
3
Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use: a systematic review.
使用聚苯乙烯磺酸纳（Kayexalate）的胃肠道不良事件：系统评价。
Am J Med. 2013 Mar;126(3):264.e9-24. doi: 10.1016/j.amjmed.2012.08.016. Epub 2013 Jan 12.
4
Association of prescription of oral sodium polystyrene sulfonate with sorbitol in an inpatient setting with colonic necrosis: a retrospective cohort study.口服聚苯乙烯磺酸钠和山梨醇处方与住院患者结肠坏死的关联：一项回顾性队列研究。
Am J Kidney Dis. 2012 Sep;60(3):409-16. doi: 10.1053/j.ajkd.2012.04.023. Epub 2012 Jun 9.
5
Colonic necrosis due to sodium polystyrene sulfate (Kayexalate).聚苯乙烯磺酸钠（降钾树脂）导致的结肠坏死。
Am J Emerg Med. 2009 Jul;27(6):753.e1-2. doi: 10.1016/j.ajem.2008.10.002.
6
Intestinal necrosis due to sodium polystyrene sulfonate (Kayexalate) in sorbitol.山梨醇中聚苯乙烯磺酸钠（降钾树脂）导致的肠坏死。
South Med J. 2009 May;102(5):493-7. doi: 10.1097/SMJ.0b013e31819e8978.
7
Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings.接受山梨醇聚苯乙烯磺酸钠（降钾树脂）治疗的患者上消化道损伤：临床、内镜及组织病理学 findings。 （原文“findings”此处直接保留英文，因为其确切含义需结合上下文确定，暂无法准确翻译）
Am J Surg Pathol. 2001 May;25(5):637-44. doi: 10.1097/00000478-200105000-00011.
8
Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol.聚苯乙烯磺酸钠-山梨醇诱发的急性腹痛伴结肠坏死
South Med J. 2000 May;93(5):511-3.
9
Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients.与山梨醇合用的聚苯乙烯磺酸钠（降钾树脂）可导致尿毒症患者发生肠坏死。
Can J Gastroenterol. 1997 Oct;11(7):573-7. doi: 10.1155/1997/370814.
10
Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition.尿毒症患者因山梨醇聚苯乙烯磺酸钠（降钾树脂）导致的胃肠道坏死：一种未被充分认识的病症。
Am J Surg Pathol. 1997 Jan;21(1):60-9. doi: 10.1097/00000478-199701000-00007.