Travers Paul, Goodman Alexandra, Poiesz Bernard
Internal Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Case Rep Oncol. 2021 Sep 15;14(3):1310-1314. doi: 10.1159/000512827. eCollection 2021 Sep-Dec.
Tumor lysis syndrome (TLS) is the most common hematologic emergency encountered during the treatment of high-grade malignancies. While it can lead to death, the prognosis is typically excellent if caught early on in the course. Risk stratification prior to treatment initiation is paramount in deciding the utility of prophylaxis and ultimately in reducing morbidity and mortality. The following case describes the development of TLS in a patient categorized as low risk and highlights the need for further elucidation of a unified risk stratification system.
肿瘤溶解综合征(TLS)是治疗高级别恶性肿瘤时最常见的血液学急症。虽然它可能导致死亡,但如果在病程早期发现,预后通常良好。在开始治疗前进行风险分层对于确定预防措施的效用以及最终降低发病率和死亡率至关重要。以下病例描述了一名被归类为低风险患者发生的TLS,并强调了进一步阐明统一风险分层系统的必要性。