Fliney Gregory, Ahmed Osama, Young Benjamin, Teng Christopher, Pointdujour-Lim Renelle
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, USA.
Yale University School of Medicine, New Haven, Connecticut, USA.
Case Rep Ophthalmol. 2021 Sep 20;12(3):791-796. doi: 10.1159/000518804. eCollection 2021 Sep-Dec.
Uveal melanoma is the most common primary intraocular tumor in adults and can have varying presentations, although it is frequently asymptomatic. One rare presentation of uveal melanoma is neovascular glaucoma (NVG). We present a case of a 20-year-old male who presented with 2 weeks of left eye redness and decreased vision who was found to have NVG. He was referred for evaluation of glaucoma. Fundoscopic and ultrasonographic examination revealed a mushroom-shaped choroidal mass with low internal reflectivity consistent with choroidal melanoma. The patient underwent enucleation, and metastatic workup revealed hepatic metastases. The patient died 18 months after initial diagnosis. This case emphasizes the importance of a complete ophthalmic evaluation in cases presenting with NVG of unclear etiology to exclude the presence of a potentially life-threatening intraocular tumor.
葡萄膜黑色素瘤是成人最常见的原发性眼内肿瘤，尽管通常无症状，但可有多种表现形式。葡萄膜黑色素瘤的一种罕见表现是新生血管性青光眼（NVG）。我们报告一例20岁男性患者，因左眼发红和视力下降2周就诊，被诊断为NVG。他因青光眼转诊评估。眼底镜和超声检查发现一个蘑菇状脉络膜肿物，内部反射率低，符合脉络膜黑色素瘤。患者接受了眼球摘除术，转移灶检查发现肝转移。患者在初次诊断后18个月死亡。该病例强调了对于病因不明的NVG患者进行全面眼科评估以排除潜在危及生命的眼内肿瘤的重要性。
