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富含益生菌和甜菜根的搅拌型酸奶的特性及其在实验性2型糖尿病中的治疗潜力

Characterization of stirred yoghurt enriched with probiotics and beetroot and its therapeutic potential in experimental type 2 diabetes.

作者信息

Mohamed Doha A, El-Sayed Hoda S, El-Gawad Mona A M Abd, Abdelgayed Sherein S, Hamed Ibrahim M, Mohamed Rasha S

机构信息

Nutrition and Food Sciences Department, National Research Centre, Cairo, Egypt.

Dairy Department, National Research Centre, Dokki, Cairo, Egypt.

出版信息

Acta Sci Pol Technol Aliment. 2021 Oct-Dec;20(4):429-448. doi: 10.17306/J.AFS.0953.

Abstract

BACKGROUND

Type-2 diabetes is the most prevalent metabolic disease, which calls for researchers to find many natural products that are effective in fighting diabetes and its complications.

METHODS

Stirred yoghurt samples were prepared, enriched with probiotics, and fortified with either 1% or 2% of the fine powder of beetroots. The chemical, physical, sensorial, and microbial properties of the yoghurt samples were studied over a 15-day storage period. The total phenolic compounds, flavonoids, antioxidant activity as well as the reducing power of the dried beetroot and the yoghurt samples were assessed.The prepared yoghurt samples were evaluated in type 2 diabetic rats.

RESULTS

Fortification with beetroot led to an increase of the total phenolic compounds, antioxidant activity, and the probiotic counts in the prepared yoghurt. The intervention with the prepared yoghurt samples resulted in an increase in the number of beneficial bacteria in diabetic rats’ feces, hypoglycemic effect, and suppression in the elevation of C-reactive protein (CRP) and thyroid stimulating hormone (TSH).

CONCLUSIONS

This study suggests that stirred yoghurt enriched with probiotics and fortified with beetroot have therapeutic potential for type 2 diabetes.

摘要

背景

2型糖尿病是最常见的代谢性疾病,这就要求研究人员寻找许多对对抗糖尿病及其并发症有效的天然产物。

方法

制备搅拌型酸奶样品,添加益生菌,并添加1%或2%的甜菜根细粉进行强化。在15天的储存期内研究酸奶样品的化学、物理、感官和微生物特性。评估了干燥甜菜根和酸奶样品中的总酚类化合物、黄酮类化合物、抗氧化活性以及还原能力。对制备好的酸奶样品在2型糖尿病大鼠中进行评估。

结果

用甜菜根强化导致制备的酸奶中总酚类化合物、抗氧化活性和益生菌数量增加。用制备的酸奶样品进行干预导致糖尿病大鼠粪便中有益细菌数量增加、降血糖作用以及抑制C反应蛋白(CRP)和促甲状腺激素(TSH)升高。

结论

本研究表明,富含益生菌并添加甜菜根强化的搅拌型酸奶对2型糖尿病具有治疗潜力。

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