2019 年冠状病毒病疫苗突破性感染，2021 年 8 月前在梅奥诊所佛罗里达州需要住院治疗。
Coronavirus Disease 2019 Vaccine-Breakthrough Infections Requiring Hospitalization in Mayo Clinic Florida Through August 2021.
机构信息
Division of Infectious Diseases, Mayo Clinic, Jacksonville, Florida, USA.
Division of Hospital Internal Medicine, Mayo Clinic, Jacksonville, Florida, USA.
出版信息
Clin Infect Dis. 2022 Aug 24;75(1):e892-e894. doi: 10.1093/cid/ciab932.
Abstract
We characterized coronavirus disease 2019 (COVID-19) breakthrough cases admitted to a single center in Florida. With the emergence of delta variant, an increased number of hospitalizations was seen due to breakthrough infections. These patients were older and more likely to have comorbidities. Preventive measures should be maintained even after vaccination.
摘要
我们对佛罗里达州一家单一中心收治的 2019 年冠状病毒病（COVID-19）突破性病例进行了特征描述。随着 delta 变异株的出现，由于突破性感染，住院人数有所增加。这些患者年龄更大，更有可能合并症。即使接种疫苗后，也应保持预防措施。
相似文献
1
Coronavirus Disease 2019 Vaccine-Breakthrough Infections Requiring Hospitalization in Mayo Clinic Florida Through August 2021.2019 年冠状病毒病疫苗突破性感染，2021 年 8 月前在梅奥诊所佛罗里达州需要住院治疗。
Clin Infect Dis. 2022 Aug 24;75(1):e892-e894. doi: 10.1093/cid/ciab932.
2
Low antispike antibody levels correlate with poor outcomes in COVID-19 breakthrough hospitalizations.低抗刺突抗体水平与 COVID-19 突破性住院治疗的不良结局相关。
J Intern Med. 2022 Jul;292(1):127-135. doi: 10.1111/joim.13471. Epub 2022 Mar 24.
3
The Risk of Hospitalization and Mortality After Breakthrough SARS-CoV-2 Infection by Vaccine Type: Observational Study of Medical Claims Data.突破性 SARS-CoV-2 感染后不同疫苗类型的住院和死亡风险：医疗索赔数据的观察性研究。
JMIR Public Health Surveill. 2022 Nov 8;8(11):e38898. doi: 10.2196/38898.
4
Vaccine breakthrough infections in veterans hospitalized with coronavirus infectious disease-2019: A case series.新冠病毒 2019 感染住院退伍军人的疫苗突破性感染：病例系列。
Am J Infect Control. 2022 Mar;50(3):273-276. doi: 10.1016/j.ajic.2021.10.003. Epub 2021 Oct 13.
5
Severe Acute Respiratory Syndrome Coronavirus 2 Delta Vaccine Breakthrough Transmissibility in Alachua County, Florida.佛罗里达州阿拉楚阿县严重急性呼吸综合征冠状病毒 2 型德尔塔疫苗突破性传播。
Clin Infect Dis. 2022 Oct 29;75(9):1618-1627. doi: 10.1093/cid/ciac197.
6
Increased delta variant SARS-CoV-2 infections in a highly vaccinated medical center in Japan.日本一家高接种率的医疗机构中 delta 变异株 SARS-CoV-2 感染增加。
Vaccine. 2022 May 20;40(23):3103-3108. doi: 10.1016/j.vaccine.2022.04.029. Epub 2022 Apr 12.
7
Breakthrough COVID-19 Infections After mRNA Vaccination in Solid Organ Transplant Recipients in Miami, Florida.佛罗里达州迈阿密实体器官移植受者接种mRNA疫苗后出现的突破性新冠病毒感染情况。
Transplantation. 2021 Oct 1;105(10):e139-e141. doi: 10.1097/TP.0000000000003902.
8
Association of BNT162b2 Vaccine Third Dose Receipt With Incidence of SARS-CoV-2 Infection, COVID-19-Related Hospitalization, and Death Among Residents of Long-term Care Facilities, August to October 2021.2021 年 8 月至 10 月，BNT162b2 疫苗第三剂接种与长期护理机构居民 SARS-CoV-2 感染、COVID-19 相关住院和死亡的相关性。
JAMA Netw Open. 2022 Jul 1;5(7):e2219940. doi: 10.1001/jamanetworkopen.2022.19940.
9
An Outbreak of Breakthrough Infections by the SARS-CoV-2 Delta Variant in a Psychiatric Closed Ward.一起德尔塔变异株引起的精神科封闭病房突破性感染事件
J Korean Med Sci. 2022 Jan 24;37(4):e28. doi: 10.3346/jkms.2022.37.e28.
10
Postvaccination infections among staff of a tertiary care hospital after vaccination with severe acute respiratory syndrome coronavirus 2 vector and mRNA-based vaccines.接种严重急性呼吸综合征冠状病毒 2 载体疫苗和基于 mRNA 的疫苗后，一家三级保健医院工作人员的疫苗接种后感染。
Clin Microbiol Infect. 2022 Apr;28(4):596-601. doi: 10.1016/j.cmi.2021.11.023. Epub 2021 Dec 13.
引用本文的文献
1
Immune Responses Against SARS-CoV-2 in Previously SARS-CoV-2-Infected Individuals after Receiving a Single Dose of CoronaVac or ChAdOx-1 Vaccine.既往感染过严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的个体在接种一剂科兴新冠疫苗（CoronaVac）或牛津-阿斯利康新冠疫苗（ChAdOx-1）后的免疫反应
Infect Chemother. 2025 Jun;57(2):274-287. doi: 10.3947/ic.2024.0145. Epub 2025 Apr 16.
2
Epidemiology, clinical features and outcomes of hospitalized patients with COVID-19 by vaccination status: a multicenter historical cohort study.接种疫苗状况对 COVID-19 住院患者的流行病学、临床特征和结局的影响：一项多中心历史队列研究。
Virol J. 2024 Mar 21;21(1):71. doi: 10.1186/s12985-024-02325-x.
3
The descriptive epidemiology of pre-omicron SARS-CoV-2 breakthrough infections and severe outcomes in Manitoba, Canada.加拿大曼尼托巴省新冠病毒奥密克戎变异株出现之前的突破性感染及严重后果的描述性流行病学研究
Front Epidemiol. 2024 Jan 12;3:1248847. doi: 10.3389/fepid.2023.1248847. eCollection 2023.
4
Profile and Outcomes of Hospitalized COVID-19 Patients during the Prevalence of the Omicron Variant According to the Brazilian Regions: A Retrospective Cohort Study from 2022.根据巴西各地区情况，2022年奥密克戎变异株流行期间住院COVID-19患者的概况及结局：一项回顾性队列研究
Vaccines (Basel). 2023 Oct 5;11(10):1568. doi: 10.3390/vaccines11101568.
5
Upregulated CD8 MAIT cell differentiation and gene expression after inactivated SARS-CoV-2 vaccination identified by single-cell sequencing.单细胞测序鉴定灭活 SARS-CoV-2 疫苗接种后 CD8 MAIT 细胞分化和基因表达上调。
Front Immunol. 2023 Aug 15;14:1174406. doi: 10.3389/fimmu.2023.1174406. eCollection 2023.
6
Levels and durability of neutralizing antibodies against SARS-CoV-2 Omicron and other variants after ChAdOx-1 or BNT162b2 booster in CoronaVac-primed elderly individuals.在科兴疫苗初免的老年个体中，接种ChAdOx-1或BNT162b2加强针后针对新冠病毒奥密克戎及其他变体的中和抗体水平和持久性。
Heliyon. 2023 Apr;9(4):e15653. doi: 10.1016/j.heliyon.2023.e15653. Epub 2023 Apr 20.
7
Risk factors for severe Covid-19 breakthrough infections: an observational longitudinal study.严重新冠突破性感染的风险因素：一项观察性纵向研究。
BMC Infect Dis. 2022 Nov 28;22(1):894. doi: 10.1186/s12879-022-07859-5.
8
Investigating transmission of SARS-CoV-2 using novel face mask sampling: a protocol for an observational prospective study of index cases and their contacts in a congregate setting.采用新型口罩采样调查 SARS-CoV-2 的传播：在聚集环境中对索引病例及其接触者进行观察性前瞻性研究的方案。
BMJ Open. 2022 Nov 23;12(11):e061029. doi: 10.1136/bmjopen-2022-061029.
9
Epidemiological and clinical characteristics of vaccinated COVID-19 patients: A meta-analysis and systematic review.接种 COVID-19 疫苗患者的流行病学和临床特征：荟萃分析和系统评价。
Int J Immunopathol Pharmacol. 2022 Jan-Dec;36:3946320221141802. doi: 10.1177/03946320221141802.
10
Profile of Brazilian inpatients with COVID-19 vaccine breakthrough infection and risk factors for unfavorable outcome.巴西新冠病毒疫苗突破性感染住院患者概况及不良结局的危险因素
Rev Panam Salud Publica. 2022 Aug 18;46:e106. doi: 10.26633/RPSP.2022.106. eCollection 2022.
Zotero 插件