Radiology Department, St. James's Hospital, James's Street, Dublin 8, Ireland.
Department of Upper GI Surgery, St. James's Hospital, James's Street, Dublin 8, Ireland.
Ir J Med Sci. 2022 Oct;191(5):2041-2046. doi: 10.1007/s11845-021-02818-6. Epub 2021 Nov 2.
The Sentry bioconvertible IVC filter (Boston Scientific, MA, USA) contains a bioabsorbable filament which hydrolyses after 60 days, allowing the arms of the filter to spring open, retract into the vessel wall and endothelialise, leaving an unobstructed IVC lumen.It is a novel treatment option for patients at transient risk of pulmonary emboli with a contraindication to anticoagulation. The device provides similar protection to other currently available devices against pulmonary emboli with minimal complications. It represents an effective alternative to retrievable filters, the removal of which is variously not attempted, not possible or associated with high complication rates.We review the literature which underpins the development of the bioconvertible filter. We describe our first deployment of the filter in an 85-year-old female with gastric malignancy (who subsequently underwent a subtotal gastrectomy) with a history of anaemia and previous pulmonary emboli. The availability of a bioconvertible filter constitutes a further step forward in the management of patients with potential or active thromboembolic disease.
Sentry 可转化型下腔静脉滤器（波士顿科学，马萨诸塞州，美国）含有可生物吸收的细丝，在 60 天后水解，允许滤器的臂弹开，缩回血管壁并内皮化，留下通畅的下腔静脉管腔。它是一种针对暂时有肺栓塞风险但有抗凝禁忌的患者的新型治疗选择。该设备在预防肺栓塞方面提供了与其他现有设备相似的保护，且并发症极少。它是可回收滤器的有效替代品，因为可回收滤器的取出要么未尝试、要么不可能或与高并发症发生率相关。我们回顾了支持可转化型滤器开发的文献。我们描述了我们在一位 85 岁女性中的首次应用，该女性患有胃癌（随后接受了胃大部切除术），存在贫血和既往肺栓塞病史。可转化型滤器的应用是在管理有潜在或活动性血栓栓塞性疾病的患者方面的又一进步。
