Pu Y, Yao Q M, Zhong J J, Yu C M
The People's Hospital of Chuxiong Yi Autonomous Prefecture, Chuxiong 675000, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2021 Oct 20;39(10):787-788. doi: 10.3760/cma.j.cn121094-20201221-00707.
Mushroom poisoning with amatoxins can cause liver dysfunction in patients, and death in severe cases. The amatoxins detection by enzyme-linked immunosorbent assay (ELISA) can help early clinical diagnosis. Three patients were identified as α-amatoxin containing mushroom poisoning by ELISA. The first symptoms of patients was gastrointestinal symptoms, and liver function damage occured later. One patient gave up treatment and died. After received supportive treatments such as adsorption of toxins, catharsis, fluid supplementation to promote toxin metabolism and liver protection, 2 patients were recovered and discharged.
鹅膏毒素引起的蘑菇中毒可导致患者肝功能障碍,严重时可导致死亡。通过酶联免疫吸附测定(ELISA)检测鹅膏毒素有助于早期临床诊断。通过ELISA鉴定出3例含有α-鹅膏毒素的蘑菇中毒患者。患者的首发症状为胃肠道症状,随后出现肝功能损害。1例患者放弃治疗后死亡。在接受了毒素吸附、导泻、补液促进毒素代谢及保肝等支持治疗后,2例患者康复出院。