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双能X线吸收法与基层医疗中骨折风险评估的临床挑战。

DXA and clinical challenges of fracture risk assessment in primary care.

作者信息

Williams Susan, Khan Leila, Licata Angelo A

机构信息

Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH.

Emeritus Consultant Staff, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH

出版信息

Cleve Clin J Med. 2021 Nov 2;88(11):615-622. doi: 10.3949/ccjm.88a.20199.

DOI:10.3949/ccjm.88a.20199
PMID:34728487
Abstract

Dual-energy x-ray absorptiometry (DXA) can detect bone mineral density loss before it can be identified on usual skeletal radiography, making it possible to diagnose osteoporosis in postmenopausal women and older men before clinical fractures arise. However, when DXA is used outside these populations or if the clinical picture does not match the reported T-scores, mistakes can arise in interpreting results and determining the need for pharmaceutical therapy.

摘要

双能X线吸收测定法(DXA)能够在常规骨骼X线摄影发现骨矿物质密度降低之前检测到这种变化,从而有可能在绝经后女性和老年男性发生临床骨折之前诊断骨质疏松症。然而,当在这些人群之外使用DXA时,或者如果临床表现与报告的T值不匹配,在解释结果和确定药物治疗需求时可能会出现错误。

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