Department of Ophthalmology, Peking University Third Hospital, Northgarden Road 49, Haidian District, Beijing, 100191, China.
International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, Ruprecht-Karls University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Sci Rep. 2021 Nov 2;11(1):21436. doi: 10.1038/s41598-021-01051-6.
An Intraocular Lens (IOL) fixated on the iris either anteriorly, as a phakic IOL, or posteriorly, as an aphakic IOL, can influence pupil motility. In this interventional case series study, we evaluated pupil size under different levels of illumination (scotopic = 0.04 lx, low-mesopic = 0.4 lx and high-mesopic = 4 lx) for anterior iris-claw IOL fixation for correcting myopia or hyperopia (IFPH), retropupillary iris-claw IOL fixation to correct aphakia or as treatment for late in-the-bag IOL dislocation/subluxation (IFRP), and capsular-fixation IOL in-the-bag implantation (IB). Pupil size was measured preoperatively for the IFPH- and IB-group as well as 6 months after surgery for all groups. We analyzed a total of 70 eyes: 22 eyes of 11 patients with phakic IOLs, 22 eyes of 20 patients in the IFRP group and 26 eyes of 13 patients in the IB group. Both IFPH and IB showed a smaller postoperative scotopic pupil size, compared with the preoperative values. When compared to postoperative values of IB and IFPH, IFRP showed a significantly smaller postoperative scotopic pupil size (IFPH: 5.89 ± 0.83 mm, IFRP: 4.37 ± 0.83 mm, IB: 5.34 ± 0.98 mm, p < 0.001) while no differences were seen at high-mesopic lighting. Neither of the surgical techniques seems to impair the constriction of the pupil.
虹膜前或虹膜后固定的人工晶状体（IOL），如前房型有晶状体眼人工晶状体（phakic IOL）或后房型无晶状体眼人工晶状体（aphakic IOL），都可能影响瞳孔运动。在这项介入性病例系列研究中，我们评估了不同光照水平（暗视 = 0.04 lx、低中视 = 0.4 lx 和高中视 = 4 lx）下，用于矫正近视或远视的虹膜前爪型 IOL 固定（IFPH）、后巩膜虹膜扣型 IOL 固定以矫正无晶状体眼或治疗晚期囊袋内 IOL 脱位/半脱位（IFRP）以及囊袋内植入的固定型 IOL（IB）的瞳孔大小。IFPH 和 IB 组在术前和所有组术后 6 个月测量了瞳孔大小。我们分析了总共 70 只眼：22 只眼为 11 例有晶状体眼患者，22 只眼为 20 例 IFRP 组患者，26 只眼为 13 例 IB 组患者。IFPH 和 IB 术后暗视瞳孔均较术前小。与 IB 和 IFPH 的术后值相比，IFRP 显示术后暗视瞳孔明显较小（IFPH：5.89 ± 0.83 mm，IFRP：4.37 ± 0.83 mm，IB：5.34 ± 0.98 mm，p < 0.001），而在高中视照明下则没有差异。这两种手术技术似乎都不会影响瞳孔的收缩。
