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鸡蛋蛋白补充剂可改善参加集体用餐点或成人学习中心的社区居住老年女性的上半身肌肉力量和蛋白质摄入量:一项试点随机对照试验。

Egg protein supplementation improved upper body muscle strength and protein intake in community-dwelling older adult females who attended congregate meal sites or adult learning centers: A pilot randomized controlled trial.

机构信息

College for Health, Community and Policy, 12346University of Texas at San Antonio, One UTSA Circle, San Antonio, TX.

School of Family and Consumer Sciences, Nutrition and Foods Program, 377659Texas State University, San Marcos, Texas, USA.

出版信息

Nutr Health. 2022 Dec;28(4):611-620. doi: 10.1177/02601060211051592. Epub 2021 Nov 3.

DOI:10.1177/02601060211051592
PMID:34730461
Abstract

Older adults that utilize community-based nutrition services are at higher nutritional risk than the general aging population, yet studies on the efficacy of protein interventions in this population are lacking. A double-blinded randomized controlled pilot study trial evaluated the impact of egg white protein supplementation on muscle mass, strength, and physical function in predominantly low-income Latina community-dwelling adult females aged 60 or older with reduced muscle strength or function. Participants (mean age = 73.6  ±  8.3 years) were randomly assigned to receive a daily dried egg white (20 g protein) or isocaloric maltodextrin supplement for 6 months (n = 16 intervention; n = 13 control). The primary outcome measure was appendicular skeletal muscle mass. Secondary outcomes were measures of muscle strength and function and dietary protein intake. Comparisons of baseline demographics were conducted using -tests and χ or Fisher's exact tests. Differences between groups were assessed using general linear models, adjusted for baseline values, and differences within groups were assessed using paired -tests or Kruskal-Wallis. No significant between-group differences were found for all measures, but protein intake, handgrip strength, and the number of arm curls significantly improved in the intervention group. Under-recruitment of study participants and a high dropout rate impacted the ability of this study to detect significant differences between groups. Daily egg white protein supplementation increases protein intake and supports upper body physical function in older adults, but additional studies are needed to investigate its role in the prevention of age-related muscle mass decline in older adults. Trial #NCT03530774 (https://clinicaltrials.gov/ct2/show/NCT03530774).

摘要

利用社区营养服务的老年人比一般老年人口的营养风险更高,但在该人群中缺乏关于蛋白质干预效果的研究。一项双盲随机对照试验研究评估了蛋清蛋白补充剂对肌肉质量、力量和身体功能的影响,研究对象为肌肉力量或功能下降、年龄在 60 岁或以上的、以拉丁裔为主的低收入社区居住的成年女性。参与者(平均年龄 73.6±8.3 岁)被随机分配接受每日干蛋清(20 克蛋白质)或等热量麦芽糊精补充剂,为期 6 个月(n=16 干预组;n=13 对照组)。主要结局测量指标为四肢骨骼肌质量。次要结局指标为肌肉力量和功能以及膳食蛋白质摄入量。使用 t 检验和 χ 检验或 Fisher 确切检验比较基线人口统计学数据。使用一般线性模型评估组间差异,调整基线值,并使用配对 t 检验或 Kruskal-Wallis 检验评估组内差异。所有指标均未发现组间差异显著,但干预组的蛋白质摄入量、握力和手臂卷曲次数明显增加。研究参与者招募不足和高辍学率影响了本研究检测组间差异的能力。每日蛋清蛋白补充剂可增加蛋白质摄入量并支持老年人的上半身身体功能,但需要进一步研究其在预防老年人与年龄相关的肌肉质量下降中的作用。试验 #NCT03530774(https://clinicaltrials.gov/ct2/show/NCT03530774)。

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