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贫血和水肿作为囊性纤维化的首发症状:病例报告

Anemia and edema as presenting signs in cystic fibrosis: case report.

作者信息

Monzon C M, Woodruff C W

出版信息

J Med. 1986;17(2):135-41.

PMID:3473159
Abstract

Anemia, edema, and length and weight below the 10th tile were the presenting signs in an infant with cystic fibrosis. She had a peripheral blood smear characterized by poikylocytosis, acanthocytosis and anisocytosis; low serum total proteins, albumin, and tocopherol/total lipid ratio. Following two months of treatment with oral pancreatic replacement therapy and tocopherol, her hemoglobin concentration, serum proteins and tocopherol/total lipid ratio returned to normal. The peripheral blood smear showed normal red cell morphology and her length and weight were above the 50th percentile. The mechanisms of anemia in cystic fibrosis patients are discussed.

摘要

一名患有囊性纤维化的婴儿出现贫血、水肿以及身长和体重低于第十百分位数等症状。她的外周血涂片表现为异形红细胞症、棘形红细胞症和红细胞大小不均;血清总蛋白、白蛋白以及生育酚/总脂质比值偏低。经过两个月的口服胰腺替代疗法和生育酚治疗后,她的血红蛋白浓度、血清蛋白以及生育酚/总脂质比值恢复正常。外周血涂片显示红细胞形态正常,且她的身长和体重高于第五十百分位数。本文讨论了囊性纤维化患者贫血的机制。

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1
Anemia and edema as presenting signs in cystic fibrosis: case report.贫血和水肿作为囊性纤维化的首发症状:病例报告
J Med. 1986;17(2):135-41.
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Relative anemia and iron deficiency in cystic fibrosis.囊性纤维化中的相对性贫血和铁缺乏
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引用本文的文献

1
Early severe anemia as the first sign of cystic fibrosis.早期严重贫血作为囊性纤维化的首发症状
Eur J Pediatr. 2016 Sep;175(9):1157-1163. doi: 10.1007/s00431-016-2752-4. Epub 2016 Aug 5.