University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Ear Nose Throat J. 2024 May;103(5):NP247-NP251. doi: 10.1177/01455613211051651. Epub 2021 Nov 3.
Immunoglobulin G4 (IgG4)-related disease is an immune-mediated disorder that commonly manifests in the salivary glands. As a recently described disorder, the description and classification of IgG4-related disease is an ongoing process. Diagnosis of IgG4-related disease requires integration of clinical history, histopathology, and radiographic findings, including ultrasonography and sialography. In this case report, we correlate parotid ultrasonographic and sialographic findings in a patient with proven IgG4-related disorder confirmed from analysis of previous submandibular gland resections. We aim to highlight the utility of multimodality imaging in the diagnosis of IgG4-related disease.
免疫球蛋白 G4（IgG4）相关疾病是一种免疫介导的疾病，常发生于唾液腺。作为一种最近描述的疾病，IgG4 相关疾病的描述和分类仍在不断发展。IgG4 相关疾病的诊断需要整合临床病史、组织病理学和影像学表现，包括超声和唾液腺造影。在本病例报告中，我们对经先前颌下腺切除分析证实为 IgG4 相关疾病的患者的腮腺超声和唾液腺造影结果进行了相关性分析。我们旨在强调多模态成像在 IgG4 相关疾病诊断中的应用。
