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经口手术治疗头颈部癌症后的生活质量和健康相关效用。

Quality of life and health-related utility after trans-oral surgery for head and neck cancers.

机构信息

Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.

Department of Otolaryngology - Head and Neck Surgery, CHUV, UNIL, Lausanne, Switzerland.

出版信息

Health Qual Life Outcomes. 2021 Nov 3;19(1):250. doi: 10.1186/s12955-021-01836-3.

Abstract

PURPOSE

The purpose of this study was to assess utility coefficients of health states following two minimally invasive surgical approaches for head and neck cancer, namely trans-oral robotic surgery and trans-oral laser microsurgery. Those utility coefficients will be later exploited in an economic evaluation study comparing the two approaches.

METHODS

The above cited economic evaluation will be done from the Swiss healthcare system perspective and, as such, Swiss healthcare professionals were interviewed to elicit utility coefficients. Health states, ranging from remission to palliative care, were described using clinical vignettes. A computerized tool (UceWeb) implementing standard gamble and rating scale methods was used.

RESULTS

Utility coefficients for 18 different health states were elicited with the two methods from 47 individuals, for a total of 1692 values. Elicited values varied from 0.980 to 0.213. Comparison with values elicited in previous studies show the need for population-specific elicitation, mainly for the worst health states.

CONCLUSION

Herein we report health utility coefficients for the Swiss population for health states following minimally invasive trans-oral surgery. This study provides utility values that can be used not only for a specific cost-utility analysis, but also for future studies involving the same health states.

摘要

目的

本研究旨在评估两种用于头颈部癌症的微创外科方法(经口机器人手术和经口激光微创手术)后健康状况的效用系数。这些效用系数将随后用于比较两种方法的经济评估研究中。

方法

上述经济评估将从瑞士医疗保健系统的角度进行,因此,采访了瑞士医疗保健专业人员以获取效用系数。使用临床病例描述了从缓解到姑息治疗的 18 种不同健康状况。使用实现标准博弈和评分量表方法的计算机工具(UceWeb)进行了评估。

结果

使用两种方法从 47 名个体中获得了 18 种不同健康状况的效用系数,共计 1692 个值。得出的值从 0.980 到 0.213 不等。与先前研究中得出的值进行比较表明,需要进行特定于人群的评估,主要是针对最差的健康状况。

结论

本文报告了瑞士人群在微创经口手术后健康状况的健康效用系数。本研究提供了不仅可用于特定的成本效益分析,还可用于涉及相同健康状况的未来研究的效用值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4932/8565022/d77f57cba4e5/12955_2021_1836_Fig1_HTML.jpg

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