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康莱特注射液在激励护理干预下应用于晚期阴茎癌患者的疗效及其对治疗依从性的影响

Efficacy of Applying Kanglaite Injection under Incentive Nursing Intervention in Treating Patients with Advanced Penile Carcinoma and Its Effect on Treatment Compliance.

作者信息

Wang Juan, Liu Qingyan, Hong Mei, Li Ge, Cheng Yong

机构信息

Department of Operating Room, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Department of Urology Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

出版信息

Evid Based Complement Alternat Med. 2021 Oct 25;2021:4114658. doi: 10.1155/2021/4114658. eCollection 2021.

Abstract

OBJECTIVE

To explore the efficacy of applying Kanglaite (KLT) injection under incentive nursing intervention (INI) in treating patients with advanced penile carcinoma and its effect on patient treatment compliance.

METHODS

The clinical data of 120 patients with advanced penile carcinoma treated in the Affiliated Hospital of Southwest Medical University from February 2019 to February 2020 were retrospectively analyzed, and the patients were equally divided into the experimental group ( = 60) and control group ( = 60) according to their admission order. All patients received the KLT injection treatment; those in the control group accepted the conventional nursing; and on this basis, those in the experimental group accepted INI, including psychological nursing intervention, which was conducted concurrently with the treatment, to compare their short-term efficacy, treatment compliance, degree of cancer-related fatigue (Brief Fatigue Inventory), and negative emotion scores (Hospital Anxiety and Depression Scale) between the two groups.

RESULTS

Compared with the control group, the experimental group presented a significantly higher objective remission rate (58.3%) ( < 0.05), higher rates of excellent and good treatment compliance ( < 0.05), and lower degree of cancer-related fatigue and negative emotion scores ( < 0.001).

CONCLUSION

INI can improve the negative emotions in patients with advanced carcinoma of the penis, alleviate their degree of cancer-related fatigue, promote their treatment compliance, and achieve a more significant efficacy of applying the KLT injection treatment, so it should be promoted in practice.

摘要

目的

探讨在激励护理干预(INI)下应用康莱特(KLT)注射液治疗晚期阴茎癌患者的疗效及其对患者治疗依从性的影响。

方法

回顾性分析2019年2月至2020年2月在西南医科大学附属医院接受治疗的120例晚期阴茎癌患者的临床资料,根据入院顺序将患者平均分为实验组(n = 60)和对照组(n = 60)。所有患者均接受KLT注射液治疗;对照组接受常规护理;在此基础上,实验组接受INI,包括与治疗同时进行的心理护理干预,比较两组患者的短期疗效、治疗依从性、癌症相关疲劳程度(简明疲劳量表)和负性情绪评分(医院焦虑抑郁量表)。

结果

与对照组相比,实验组的客观缓解率显著更高(58.3%)(P < 0.05),优、良治疗依从率更高(P < 0.05),癌症相关疲劳程度和负性情绪评分更低(P < 0.001)。

结论

INI可改善晚期阴茎癌患者的负性情绪,减轻其癌症相关疲劳程度,提高其治疗依从性,使KLT注射液治疗取得更显著的疗效,故应在实践中推广应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c80f/8560245/a8367c8d3414/ECAM2021-4114658.001.jpg

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