Li Shuo, Zhang Qi-Li, Guo Rui-Jun, Lv Xiu-Zhang, Yang Xue
Department of Ultrasound Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Transl Pediatr. 2021 Sep;10(9):2325-2334. doi: 10.21037/tp-21-381.
The aim of this study was to evaluate the effect of lung ultrasound on bronchoalveolar lavage in the treatment of mycoplasma pneumonia in children.
Thirty children with mycoplasma pneumonia who were treated with medication and bronchial lavage were selected. We collected the results of laboratory and imaging examinations after admission, and the changes in lung consolidation area were examined by ultrasound before, immediately upon completion, and at 1, 3, and 7 days after bronchoalveolar lavage. The effective factors affecting bronchial lavage were analyzed through logistic regression.
Univariate regression analysis showed significant differences in the lung consolidation area at admission, before, immediately upon completion, and at 1 and 7 days after lavage, as well as in the disease course and atelectasis (or not). Multivariate analysis showed that there were statistical differences in the lung consolidation area at admission, atelectasis (or not), and disease course: lung consolidation area at admission [odds ratio (OR): 2.31512, 95% confidence interval (CI): (0.00182, 0.031775), P=0.029474], atelectasis [OR: 2.695742, 95% CI: (0.079281, 0.597218), P=0.012629], and disease course [OR: -2.43347, 95% CI: (-0.02568, -0.00211), P=0.022773].
Lung ultrasound can evaluate the effect of bronchial lavage through lung consolidation and atelectasis, which can provide a reference for clinical treatment.
本研究旨在评估肺部超声在儿童支原体肺炎支气管肺泡灌洗治疗中的作用。
选取30例接受药物治疗及支气管灌洗的支原体肺炎患儿。收集入院后实验室及影像学检查结果，在支气管肺泡灌洗前、灌洗结束即刻、灌洗后1天、3天及7天通过超声检查肺部实变面积变化。通过逻辑回归分析影响支气管灌洗的有效因素。
单因素回归分析显示，入院时、灌洗前、灌洗结束即刻、灌洗后1天及7天的肺部实变面积、病程及肺不张（有无）差异有统计学意义。多因素分析显示，入院时肺部实变面积、肺不张（有无）及病程差异有统计学意义：入院时肺部实变面积[比值比（OR）：2.31512，95%置信区间（CI）：（0.00182，0.031775），P = 0.029474]，肺不张[OR：2.695742，95%CI：（0.079281，0.597218），P = 0.012629]，病程[OR： - 2.43347，95%CI：（ - 0.02568， - 0.00211），P = 0.022773]。
肺部超声可通过肺部实变及肺不张评估支气管灌洗效果，可为临床治疗提供参考。
