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生物假体或天然主动脉瓣叶有意撕裂以预防经导管主动脉瓣置换术中医源性冠状动脉阻塞的保障措施和陷阱——BASILICA技术

Safeguards and pitfalls for Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction during transcatheter aortic valve replacement-the BASILICA technique.

作者信息

Bruce Christopher G, Greenbaum Adam B, Babaliaros Vasilis C, Rogers Toby, Lederman Robert J, Khan Jaffar M

机构信息

Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

Division of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, GA, USA.

出版信息

Ann Cardiothorac Surg. 2021 Sep;10(5):700-707. doi: 10.21037/acs-2021-tviv-26.

Abstract

Coronary artery obstruction is a devastating complication of transcatheter aortic valve replacement (TAVR). Bioprosthetic or native Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery Obstruction (BASILICA) is a transcatheter, electrosurgical technique that was developed to prevent obstruction due to sinus effacement or sinus sequestration. BASILICA creates a midline laceration of one (solo) or both (doppio) offending aortic leaflets and has been performed in over 1,000 patients at high risk for obstruction. The procedure has been studied in the prospective BASILICA IDE Trial and data from the International BASILICA Registry of 214 patients supports efficacy and safety; procedural success was achieved in 94.4% and at thirty days 95.3% were free from culprit coronary artery obstruction, all-cause mortality was 2.8% and disabling stroke was reported in only 0.5%. In this review we discuss screening for patients at high risk for coronary artery obstruction, technical details related to performing the BASILICA procedure and how to troubleshoot a BASILICA procedure.

摘要

冠状动脉阻塞是经导管主动脉瓣置换术(TAVR)的一种严重并发症。生物人工瓣膜或天然主动脉瓣叶故意撕裂以预防医源性冠状动脉阻塞(BASILICA)是一种经导管电外科技术,其开发目的是预防因窦消失或窦隔离导致的阻塞。BASILICA会在一个(单瓣)或两个(双瓣)有问题的主动脉瓣叶上造成中线撕裂,已在1000多名有阻塞高风险的患者中实施。该手术已在前瞻性BASILICA IDE试验中进行研究,来自国际BASILICA注册中心的214例患者的数据支持其有效性和安全性;手术成功率为94.4%,30天时95.3%的患者无罪犯冠状动脉阻塞,全因死亡率为2.8%,致残性中风仅报告了0.5%。在本综述中,我们讨论了冠状动脉阻塞高风险患者的筛查、与实施BASILICA手术相关的技术细节以及如何解决BASILICA手术中的问题。

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本文引用的文献

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Transcatheter Electrosurgery: JACC State-of-the-Art Review.经导管电外科:JACC 最新技术评价。
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